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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCI
All Species:
45.15
Human Site:
Y584
Identified Species:
70.95
UniProt:
P41743
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41743
NP_002731.4
596
68262
Y584
S
E
F
E
G
F
E
Y
I
N
P
L
L
M
S
Chimpanzee
Pan troglodytes
XP_001148501
597
67369
Y585
S
E
F
E
G
F
E
Y
I
N
P
L
L
L
S
Rhesus Macaque
Macaca mulatta
XP_001089400
597
68263
Y585
S
E
F
E
G
F
E
Y
I
N
P
L
L
M
S
Dog
Lupus familis
XP_535855
696
78257
Y684
S
E
F
E
G
F
E
Y
I
N
P
L
L
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62074
595
68185
Y583
S
E
F
E
G
F
E
Y
I
N
P
L
L
M
S
Rat
Rattus norvegicus
P09217
592
67715
Y580
S
E
F
E
G
F
E
Y
I
N
P
L
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506164
360
41199
I349
E
F
E
G
F
E
Y
I
N
P
L
L
M
S
A
Chicken
Gallus gallus
XP_417561
606
69931
Y594
S
E
F
E
G
F
E
Y
I
N
P
L
L
L
S
Frog
Xenopus laevis
NP_001084068
588
67442
Y576
S
E
F
E
G
F
E
Y
I
N
P
L
L
M
S
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
Y576
S
E
F
E
G
F
E
Y
I
N
P
L
L
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
F622
D
E
F
A
G
F
S
F
V
N
P
K
F
G
P
Honey Bee
Apis mellifera
XP_397273
590
68031
Y578
S
E
F
E
G
F
E
Y
V
N
P
L
L
M
S
Nematode Worm
Caenorhab. elegans
Q19266
597
68017
Y585
S
E
F
D
G
F
E
Y
V
N
P
L
Q
M
S
Sea Urchin
Strong. purpuratus
XP_780275
524
59689
I513
E
F
E
G
F
E
Y
I
N
P
L
L
M
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
E1130
V
L
S
Q
A
M
Q
E
E
F
R
G
F
S
Y
Conservation
Percent
Protein Identity:
100
66.6
96.8
84.3
N.A.
98.3
72.3
N.A.
59.9
71.4
89.7
88.7
N.A.
36.4
67.9
58.1
63.5
Protein Similarity:
100
78.5
97.4
84.9
N.A.
98.8
83.5
N.A.
60.4
83
94.4
92.9
N.A.
54
78.1
74.1
72.4
P-Site Identity:
100
93.3
100
100
N.A.
100
93.3
N.A.
6.6
93.3
100
100
N.A.
40
93.3
80
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
53.3
100
93.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
23.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
14
80
14
67
0
14
74
7
7
0
0
0
0
0
0
% E
% Phe:
0
14
80
0
14
80
0
7
0
7
0
0
14
0
0
% F
% Gly:
0
0
0
14
80
0
0
0
0
0
0
7
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
14
60
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
0
7
0
0
0
0
0
0
0
0
14
87
67
20
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
14
54
0
% M
% Asn:
0
0
0
0
0
0
0
0
14
80
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
14
80
0
0
0
7
% P
% Gln:
0
0
0
7
0
0
7
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
74
0
7
0
0
0
7
0
0
0
0
0
0
20
74
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
14
74
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _