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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MC3R
All Species:
8.18
Human Site:
S340
Identified Species:
20
UniProt:
P41968
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41968
NP_063941.3
360
40073
S340
P
L
I
Y
A
F
R
S
L
E
L
R
N
T
F
Chimpanzee
Pan troglodytes
Q9TT23
325
36628
C312
T
F
K
E
I
I
C
C
R
G
F
R
I
A
C
Rhesus Macaque
Macaca mulatta
Q864J4
317
34745
E304
I
Y
A
F
R
S
Q
E
L
R
R
T
L
K
E
Dog
Lupus familis
XP_541099
632
70219
S606
P
L
I
Y
A
F
R
S
Q
E
M
R
K
S
F
Cat
Felis silvestris
Mouse
Mus musculus
P33033
323
35788
F310
S
L
E
L
R
N
T
F
K
E
I
L
C
G
C
Rat
Rattus norvegicus
P32244
323
35847
F310
S
L
E
L
R
N
T
F
K
E
I
L
C
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509734
430
48231
S411
P
L
I
Y
A
F
R
S
L
E
M
R
K
T
F
Chicken
Gallus gallus
NP_001026186
325
36976
C312
T
F
K
E
I
I
C
C
Y
S
V
R
M
V
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_851303
327
35919
F314
S
L
E
M
R
K
T
F
K
E
I
L
C
C
F
Tiger Blowfish
Takifugu rubipres
NP_001027732
322
35956
F309
S
Q
E
M
R
K
T
F
K
E
I
F
C
C
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.1
45.2
37
N.A.
79.7
79.7
N.A.
62.3
57.5
N.A.
65.2
56.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71.9
61.6
46.9
N.A.
84.4
85
N.A.
71.6
72.5
N.A.
76.1
72.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
73.3
N.A.
13.3
13.3
N.A.
86.6
6.6
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
20
86.6
N.A.
20
20
N.A.
93.3
13.3
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
30
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
20
20
0
0
0
0
40
20
40
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
40
20
0
0
0
10
0
70
0
0
0
0
10
% E
% Phe:
0
20
0
10
0
30
0
40
0
0
10
10
0
0
40
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
20
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
30
0
20
20
0
0
0
0
40
0
10
0
0
% I
% Lys:
0
0
20
0
0
20
0
0
40
0
0
0
20
10
0
% K
% Leu:
0
60
0
20
0
0
0
0
30
0
10
30
10
0
0
% L
% Met:
0
0
0
20
0
0
0
0
0
0
20
0
10
0
0
% M
% Asn:
0
0
0
0
0
20
0
0
0
0
0
0
10
0
0
% N
% Pro:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
50
0
30
0
10
10
10
50
0
0
0
% R
% Ser:
40
0
0
0
0
10
0
30
0
10
0
0
0
10
10
% S
% Thr:
20
0
0
0
0
0
40
0
0
0
0
10
0
20
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
30
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _