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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR1B
All Species:
22.73
Human Site:
S225
Identified Species:
31.25
UniProt:
P42025
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42025
NP_005726.1
376
42293
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Chimpanzee
Pan troglodytes
XP_001155293
376
42274
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Rhesus Macaque
Macaca mulatta
XP_001101028
376
42275
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Dog
Lupus familis
XP_854473
376
42271
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5C5
376
42263
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Rat
Rattus norvegicus
P68035
377
42000
A222
K
E
K
L
C
Y
V
A
L
D
F
E
N
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509975
345
38928
D204
Y
L
R
K
E
G
Y
D
F
H
S
S
S
E
F
Chicken
Gallus gallus
P08023
377
41976
A222
K
E
K
L
C
Y
V
A
L
D
F
E
N
E
M
Frog
Xenopus laevis
P10995
377
41970
A222
K
E
K
L
C
Y
V
A
L
D
F
E
N
E
M
Zebra Danio
Brachydanio rerio
NP_998537
376
42387
S225
K
E
R
A
C
Y
L
S
L
N
P
Q
K
D
E
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
A222
K
E
K
L
C
Y
V
A
L
D
F
E
N
E
M
Fruit Fly
Dros. melanogaster
P45889
376
42701
A225
K
E
K
V
C
Y
L
A
T
N
P
Q
K
E
E
Honey Bee
Apis mellifera
XP_623834
376
42650
A225
K
E
R
A
C
Y
L
A
S
N
P
Q
K
E
E
Nematode Worm
Caenorhab. elegans
P10986
376
41759
A221
K
E
K
L
C
Y
V
A
L
D
F
E
Q
E
M
Sea Urchin
Strong. purpuratus
P53472
376
41830
A221
K
E
K
L
C
Y
V
A
L
D
F
E
Q
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P53492
377
41717
A222
K
E
K
L
A
Y
V
A
L
D
Y
E
Q
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P38673
380
42364
A223
K
E
S
V
T
Y
V
A
H
D
P
R
K
E
E
Conservation
Percent
Protein Identity:
100
99.7
99.4
98.6
N.A.
98.9
54.1
N.A.
82.9
53.8
53.8
93.6
54.1
77.1
84.8
55
55
Protein Similarity:
100
100
100
99.1
N.A.
99.7
72.9
N.A.
89.6
72.9
72.9
98.4
72.9
90.9
94.4
73.6
73.6
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
6.6
26.6
26.6
93.3
26.6
66.6
80
26.6
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
73.3
N.A.
20
73.3
73.3
100
73.3
86.6
93.3
80
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.3
N.A.
63.4
Protein Similarity:
N.A.
N.A.
N.A.
75
N.A.
80.7
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
42
6
0
0
59
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
83
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
6
0
48
0
0
0
36
0
% D
% Glu:
0
95
0
0
6
0
0
0
0
0
0
42
0
65
53
% E
% Phe:
0
0
0
0
0
0
0
0
6
0
36
0
0
0
6
% F
% Gly:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
6
6
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% I
% Lys:
95
0
48
6
0
0
0
0
0
0
0
0
53
0
0
% K
% Leu:
0
6
0
42
0
0
48
0
48
0
0
0
0
0
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
36
% M
% Asn:
0
0
0
0
0
0
0
0
0
48
0
0
24
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
53
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
48
18
0
0
% Q
% Arg:
0
0
48
0
0
0
0
0
0
0
0
6
0
0
0
% R
% Ser:
0
0
6
0
0
0
0
36
6
0
6
6
6
0
0
% S
% Thr:
0
0
0
0
6
0
0
0
6
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
48
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
95
6
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _