KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR1B
All Species:
43.03
Human Site:
S272
Identified Species:
59.17
UniProt:
P42025
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42025
NP_005726.1
376
42293
S272
P
D
L
V
G
D
E
S
E
G
L
H
E
V
V
Chimpanzee
Pan troglodytes
XP_001155293
376
42274
S272
P
D
L
V
G
D
E
S
E
G
L
H
E
V
V
Rhesus Macaque
Macaca mulatta
XP_001101028
376
42275
S272
P
D
L
V
G
D
E
S
E
G
L
H
E
V
L
Dog
Lupus familis
XP_854473
376
42271
S272
P
D
L
V
G
D
E
S
E
G
L
H
E
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5C5
376
42263
S272
P
D
L
V
G
D
E
S
E
G
L
H
E
V
L
Rat
Rattus norvegicus
P68035
377
42000
S273
P
S
F
I
G
M
E
S
A
G
I
H
E
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509975
345
38928
Y242
E
T
E
K
A
Q
Y
Y
L
P
D
G
S
T
I
Chicken
Gallus gallus
P08023
377
41976
S273
P
S
F
I
G
M
E
S
A
G
I
H
E
T
T
Frog
Xenopus laevis
P10995
377
41970
S273
P
S
F
I
G
M
E
S
A
G
I
H
E
T
A
Zebra Danio
Brachydanio rerio
NP_998537
376
42387
S272
P
D
L
I
G
D
E
S
E
G
I
H
E
V
L
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
S273
P
S
F
I
G
M
E
S
A
G
I
H
E
T
A
Fruit Fly
Dros. melanogaster
P45889
376
42701
C272
P
D
L
L
G
E
E
C
E
G
I
H
D
V
L
Honey Bee
Apis mellifera
XP_623834
376
42650
C272
P
D
L
I
G
E
E
C
E
G
L
H
E
V
L
Nematode Worm
Caenorhab. elegans
P10986
376
41759
S272
P
S
F
L
G
M
E
S
A
G
I
H
E
T
S
Sea Urchin
Strong. purpuratus
P53472
376
41830
S272
P
A
F
L
G
M
E
S
A
G
I
H
E
T
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P53492
377
41717
A273
P
S
L
I
G
M
E
A
P
G
I
H
E
T
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P38673
380
42364
Y277
P
E
I
I
G
L
E
Y
P
G
V
H
Q
I
V
Conservation
Percent
Protein Identity:
100
99.7
99.4
98.6
N.A.
98.9
54.1
N.A.
82.9
53.8
53.8
93.6
54.1
77.1
84.8
55
55
Protein Similarity:
100
100
100
99.1
N.A.
99.7
72.9
N.A.
89.6
72.9
72.9
98.4
72.9
90.9
94.4
73.6
73.6
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
46.6
N.A.
0
46.6
46.6
80
46.6
60
73.3
46.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
6.6
60
60
100
60
93.3
93.3
60
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.3
N.A.
63.4
Protein Similarity:
N.A.
N.A.
N.A.
75
N.A.
80.7
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
6
0
0
6
36
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
6
% C
% Asp:
0
48
0
0
0
36
0
0
0
0
6
0
6
0
0
% D
% Glu:
6
6
6
0
0
12
95
0
48
0
0
0
83
0
0
% E
% Phe:
0
0
36
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
95
0
0
0
0
95
0
6
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
95
0
0
0
% H
% Ile:
0
0
6
48
0
0
0
0
0
0
53
0
0
6
6
% I
% Lys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
53
18
0
6
0
0
6
0
36
0
0
0
36
% L
% Met:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
95
0
0
0
0
0
0
0
12
6
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
6
0
0
0
0
0
0
6
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
36
0
0
0
0
0
71
0
0
0
0
6
0
6
% S
% Thr:
0
6
0
0
0
0
0
0
0
0
0
0
0
48
18
% T
% Val:
0
0
0
30
0
0
0
0
0
0
6
0
0
48
18
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
6
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _