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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR1B
All Species:
33.03
Human Site:
S286
Identified Species:
45.42
UniProt:
P42025
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42025
NP_005726.1
376
42293
S286
V
A
F
A
I
H
K
S
D
M
D
L
R
R
T
Chimpanzee
Pan troglodytes
XP_001155293
376
42274
S286
V
A
F
A
I
H
K
S
D
M
D
L
R
R
T
Rhesus Macaque
Macaca mulatta
XP_001101028
376
42275
S286
L
A
F
A
I
H
K
S
D
M
D
L
R
R
T
Dog
Lupus familis
XP_854473
376
42271
S286
L
V
F
A
I
H
K
S
D
M
D
L
R
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5C5
376
42263
S286
L
A
F
A
I
H
K
S
D
M
D
L
R
R
T
Rat
Rattus norvegicus
P68035
377
42000
C287
T
Y
N
S
I
M
K
C
D
I
D
I
R
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509975
345
38928
F256
I
E
I
G
P
S
R
F
R
A
P
E
L
L
F
Chicken
Gallus gallus
P08023
377
41976
C287
T
Y
N
S
I
M
K
C
D
I
D
I
R
K
D
Frog
Xenopus laevis
P10995
377
41970
C287
A
Y
N
S
I
M
K
C
D
I
D
I
R
K
D
Zebra Danio
Brachydanio rerio
NP_998537
376
42387
S286
L
A
F
A
I
Q
K
S
D
M
D
L
R
R
T
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
C287
A
Y
N
S
I
M
K
C
D
I
D
I
R
K
D
Fruit Fly
Dros. melanogaster
P45889
376
42701
S286
L
M
Y
S
I
E
K
S
D
M
D
L
R
K
M
Honey Bee
Apis mellifera
XP_623834
376
42650
S286
L
T
Y
S
I
Q
K
S
D
L
D
L
R
K
V
Nematode Worm
Caenorhab. elegans
P10986
376
41759
C286
S
Y
N
S
I
M
K
C
D
I
D
I
R
K
D
Sea Urchin
Strong. purpuratus
P53472
376
41830
C286
C
Y
N
S
I
M
K
C
D
V
D
I
R
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P53492
377
41717
C287
T
Y
N
S
I
M
K
C
D
V
D
I
R
K
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P38673
380
42364
T291
V
V
D
S
I
N
R
T
D
L
D
L
R
R
D
Conservation
Percent
Protein Identity:
100
99.7
99.4
98.6
N.A.
98.9
54.1
N.A.
82.9
53.8
53.8
93.6
54.1
77.1
84.8
55
55
Protein Similarity:
100
100
100
99.1
N.A.
99.7
72.9
N.A.
89.6
72.9
72.9
98.4
72.9
90.9
94.4
73.6
73.6
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
33.3
N.A.
0
33.3
33.3
86.6
33.3
53.3
46.6
33.3
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
60
N.A.
13.3
60
60
93.3
60
80
80
60
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.3
N.A.
63.4
Protein Similarity:
N.A.
N.A.
N.A.
75
N.A.
80.7
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
30
0
36
0
0
0
0
0
6
0
0
0
0
0
% A
% Cys:
6
0
0
0
0
0
0
42
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
0
0
0
0
95
0
95
0
0
0
48
% D
% Glu:
0
6
0
0
0
6
0
0
0
0
0
6
0
0
0
% E
% Phe:
0
0
36
0
0
0
0
6
0
0
0
0
0
0
6
% F
% Gly:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
6
0
95
0
0
0
0
30
0
42
0
0
0
% I
% Lys:
0
0
0
0
0
0
89
0
0
0
0
0
0
53
0
% K
% Leu:
36
0
0
0
0
0
0
0
0
12
0
53
6
6
0
% L
% Met:
0
6
0
0
0
42
0
0
0
42
0
0
0
0
6
% M
% Asn:
0
0
42
0
0
6
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
6
0
0
0
0
0
6
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
6
0
0
0
95
42
0
% R
% Ser:
6
0
0
59
0
6
0
48
0
0
0
0
0
0
0
% S
% Thr:
18
6
0
0
0
0
0
6
0
0
0
0
0
0
36
% T
% Val:
18
12
0
0
0
0
0
0
0
12
0
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
42
12
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _