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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCI All Species: 36.97
Human Site: Y293 Identified Species: 90.37
UniProt: P42126 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42126 NP_001910.2 302 32816 Y293 I Q K S L Q M Y L E R L K E E
Chimpanzee Pan troglodytes XP_001172995 361 39696 Y352 I Q K S L Q M Y L E R L K E K
Rhesus Macaque Macaca mulatta XP_001084889 305 33167 Y296 I Q K S L Q L Y L E R L K E K
Dog Lupus familis XP_547179 342 36539 Y333 I Q K S L H V Y I E K L Q K K
Cat Felis silvestris
Mouse Mus musculus P42125 289 32060 Y280 I Q K S L H M Y L E K L K Q K
Rat Rattus norvegicus P23965 289 32236 Y280 I Q K S L H V Y L E K L K Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414954 308 34276 Y299 I Q K S L S T Y M E M L R K K
Frog Xenopus laevis NP_001085036 298 33189 Y290 I Q K S L Q V Y M E R L K Q R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609322 281 30975 Y270 V Q K G L G I Y L E G L K K K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796711 296 33346 Y289 V Q K H L G S Y M E K L K K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.5 80 68.7 N.A. 70.5 74.1 N.A. N.A. 58.7 59.9 N.A. N.A. 37 N.A. N.A. 44
Protein Similarity: 100 76.7 85.2 76.9 N.A. 81.4 84.7 N.A. N.A. 75.9 76.8 N.A. N.A. 55.9 N.A. N.A. 63.2
P-Site Identity: 100 93.3 86.6 53.3 N.A. 73.3 66.6 N.A. N.A. 53.3 73.3 N.A. N.A. 53.3 N.A. N.A. 46.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 80 93.3 N.A. N.A. 80 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 100 0 0 0 30 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 20 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 10 0 30 0 0 0 0 0 0 0 0 0 % H
% Ile: 80 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 100 0 0 0 0 0 0 0 40 0 80 40 80 % K
% Leu: 0 0 0 0 100 0 10 0 60 0 0 100 0 0 0 % L
% Met: 0 0 0 0 0 0 30 0 30 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 100 0 0 0 40 0 0 0 0 0 0 10 30 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 40 0 10 0 10 % R
% Ser: 0 0 0 80 0 10 10 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % T
% Val: 20 0 0 0 0 0 30 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _