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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMPO
All Species:
13.94
Human Site:
S458
Identified Species:
38.33
UniProt:
P42166
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42166
NP_003267.1
694
75492
S458
I
P
G
S
E
L
M
S
S
F
A
K
T
V
V
Chimpanzee
Pan troglodytes
XP_509288
694
75514
S458
I
P
G
S
E
L
M
S
S
F
A
K
T
V
V
Rhesus Macaque
Macaca mulatta
XP_001082600
695
75456
P458
I
P
G
S
E
L
L
P
S
S
F
A
K
T
V
Dog
Lupus familis
XP_539735
693
75491
S457
T
P
G
S
G
V
M
S
S
F
A
K
T
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61033
693
75313
S456
T
P
G
S
E
H
R
S
S
F
A
K
S
V
V
Rat
Rattus norvegicus
Q62733
452
50259
E229
Y
S
E
A
G
V
T
E
T
E
W
T
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006235
446
50163
S223
V
T
E
T
V
W
T
S
G
S
S
K
S
G
P
Frog
Xenopus laevis
NP_001079677
206
23473
Zebra Danio
Brachydanio rerio
NP_851299
657
72198
V434
V
S
K
L
S
K
P
V
L
S
Q
S
K
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.8
87.7
N.A.
78.5
36.8
N.A.
N.A.
32.7
22.7
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.8
91.7
N.A.
86.5
49.7
N.A.
N.A.
46.8
26.9
40.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
80
N.A.
73.3
0
N.A.
N.A.
13.3
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
60
86.6
N.A.
80
26.6
N.A.
N.A.
40
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
0
0
45
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
23
0
45
0
0
12
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
45
12
0
0
0
0
% F
% Gly:
0
0
56
0
23
0
0
0
12
0
0
0
0
23
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
12
0
0
0
0
0
56
23
0
0
% K
% Leu:
0
0
0
12
0
34
12
0
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
56
0
0
0
0
12
12
0
0
0
0
0
12
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% R
% Ser:
0
23
0
56
12
0
0
56
56
34
12
12
34
0
23
% S
% Thr:
23
12
0
12
0
0
23
0
12
0
0
12
34
12
0
% T
% Val:
23
0
0
0
12
23
0
12
0
0
0
0
0
45
56
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
12
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _