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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMPO
All Species:
22.73
Human Site:
S168
Identified Species:
50
UniProt:
P42167
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42167
NP_001027454.1
454
50670
S168
P
L
P
T
I
S
S
S
A
E
N
T
R
Q
N
Chimpanzee
Pan troglodytes
XP_001148998
454
50700
S168
P
L
P
T
I
S
S
S
A
E
N
T
R
Q
N
Rhesus Macaque
Macaca mulatta
XP_001082220
454
50638
S168
P
L
P
T
I
S
S
S
A
E
N
T
R
Q
N
Dog
Lupus familis
XP_866351
454
50494
S168
P
L
P
T
I
S
S
S
A
E
N
T
R
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61029
452
50276
S167
P
L
P
T
V
S
S
S
A
E
N
T
R
Q
N
Rat
Rattus norvegicus
Q62733
452
50259
S167
P
L
P
T
V
S
S
S
A
E
N
T
R
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505997
411
46465
G137
E
K
R
E
P
L
K
G
K
T
K
P
P
V
T
Chicken
Gallus gallus
NP_001006235
446
50163
D168
Q
N
G
N
N
D
S
D
Q
Y
S
D
N
E
E
Frog
Xenopus laevis
NP_001081647
518
58117
A168
Y
S
D
N
E
E
E
A
K
V
E
L
T
F
E
Zebra Danio
Brachydanio rerio
NP_851299
657
72198
E168
D
Q
Y
S
D
R
E
E
E
P
V
A
P
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01971
166
18100
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.4
94.2
N.A.
90.5
90.5
N.A.
69.3
74.6
52.9
29.8
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
100
99.7
99.3
97.1
N.A.
94.2
95.1
N.A.
77.7
84.3
65.6
44.1
N.A.
N.A.
N.A.
27
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
6.6
0
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
20
6.6
6.6
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
55
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
10
10
0
10
0
0
0
10
0
0
0
% D
% Glu:
10
0
0
10
10
10
19
10
10
55
10
0
0
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
37
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
10
0
19
0
10
0
0
0
0
% K
% Leu:
0
55
0
0
0
10
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
19
10
0
0
0
0
0
55
0
10
0
55
% N
% Pro:
55
0
55
0
10
0
0
0
0
10
0
10
19
0
10
% P
% Gln:
10
10
0
0
0
0
0
0
10
0
0
0
0
55
0
% Q
% Arg:
0
0
10
0
0
10
0
0
0
0
0
0
55
0
0
% R
% Ser:
0
10
0
10
0
55
64
55
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
55
0
0
0
0
0
10
0
55
10
0
10
% T
% Val:
0
0
0
0
19
0
0
0
0
10
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _