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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMPO All Species: 24.24
Human Site: Y394 Identified Species: 53.33
UniProt: P42167 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42167 NP_001027454.1 454 50670 Y394 S S K Y V P K Y V P L A D V K
Chimpanzee Pan troglodytes XP_001148998 454 50700 Y394 S S K Y V P K Y V P F A D V K
Rhesus Macaque Macaca mulatta XP_001082220 454 50638 Y394 S S K Y V P K Y V P L A D V K
Dog Lupus familis XP_866351 454 50494 Y394 S T K Y I P K Y V P L A D V K
Cat Felis silvestris
Mouse Mus musculus Q61029 452 50276 Y393 S S K Y V P K Y A P L A D V K
Rat Rattus norvegicus Q62733 452 50259 Y393 S S K Y V P K Y V P L A D V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505997 411 46465 V358 K I L L F V V V A I F L F L V
Chicken Gallus gallus NP_001006235 446 50163 S391 S T S S D I K S E K P S T K K
Frog Xenopus laevis NP_001081647 518 58117 V452 T S K Y V S N V S K Y T P A V
Zebra Danio Brachydanio rerio NP_851299 657 72198 T571 L S D L K Q T T S S S S F S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O01971 166 18100 R113 E E E M A A D R A S A R Q A Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.4 94.2 N.A. 90.5 90.5 N.A. 69.3 74.6 52.9 29.8 N.A. N.A. N.A. 20.4 N.A.
Protein Similarity: 100 99.7 99.3 97.1 N.A. 94.2 95.1 N.A. 77.7 84.3 65.6 44.1 N.A. N.A. N.A. 27 N.A.
P-Site Identity: 100 93.3 100 86.6 N.A. 93.3 100 N.A. 0 20 26.6 6.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 93.3 100 N.A. 6.6 33.3 33.3 13.3 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 10 0 0 28 0 10 55 0 19 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 10 0 10 0 0 0 0 0 55 0 0 % D
% Glu: 10 10 10 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 19 0 19 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 10 10 0 0 0 10 0 0 0 0 0 % I
% Lys: 10 0 64 0 10 0 64 0 0 19 0 0 0 10 64 % K
% Leu: 10 0 10 19 0 0 0 0 0 0 46 10 0 10 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 55 0 0 0 55 10 0 10 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 10 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % R
% Ser: 64 64 10 10 0 10 0 10 19 19 10 19 0 10 10 % S
% Thr: 10 19 0 0 0 0 10 10 0 0 0 10 10 0 0 % T
% Val: 0 0 0 0 55 10 10 19 46 0 0 0 0 55 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 64 0 0 0 55 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _