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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STAT1 All Species: 25.76
Human Site: S606 Identified Species: 70.83
UniProt: P42224 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42224 NP_009330.1 750 87335 S606 F L L R F S E S S R E G A I T
Chimpanzee Pan troglodytes XP_511505 786 90098 S610 F L L R F S E S S K E G G V T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848353 750 87263 S606 F L L R F S E S C R E G A I T
Cat Felis silvestris
Mouse Mus musculus P42225 749 87179 S606 F L L R F S E S S R E G A I T
Rat Rattus norvegicus P52631 770 88021 S613 F L L R F S E S S K E G G V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q6DV79 771 88152 S613 F L L R F S E S S K E G G I T
Frog Xenopus laevis Q7ZXK3 766 87581 S613 F L L R F S E S S K E G G I T
Zebra Danio Brachydanio rerio NP_571555 749 86838 E603 T F L L R F S E S N R D G A I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24151 761 86396 I619 L L R S V Y G I G T F L L R F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.8 N.A. 96.2 N.A. 92.2 51.5 N.A. N.A. 50.9 50.7 61 N.A. 25.2 N.A. N.A. N.A.
Protein Similarity: 100 69.5 N.A. 98.2 N.A. 94.9 70.7 N.A. N.A. 70.4 70.5 78.1 N.A. 46.7 N.A. N.A. N.A.
P-Site Identity: 100 80 N.A. 93.3 N.A. 100 80 N.A. N.A. 86.6 86.6 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 N.A. 93.3 N.A. 100 93.3 N.A. N.A. 93.3 93.3 13.3 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 34 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % D
% Glu: 0 0 0 0 0 0 78 12 0 0 78 0 0 0 0 % E
% Phe: 78 12 0 0 78 12 0 0 0 0 12 0 0 0 12 % F
% Gly: 0 0 0 0 0 0 12 0 12 0 0 78 56 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 12 0 0 0 0 0 56 12 % I
% Lys: 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 % K
% Leu: 12 89 89 12 0 0 0 0 0 0 0 12 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 12 78 12 0 0 0 0 34 12 0 0 12 0 % R
% Ser: 0 0 0 12 0 78 12 78 78 0 0 0 0 0 0 % S
% Thr: 12 0 0 0 0 0 0 0 0 12 0 0 0 0 78 % T
% Val: 0 0 0 0 12 0 0 0 0 0 0 0 0 23 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _