KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STAT6
All Species:
7.88
Human Site:
S67
Identified Species:
24.76
UniProt:
P42226
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42226
NP_003144.3
847
94135
S67
T
V
Q
H
L
Q
A
S
V
G
E
Q
G
E
G
Chimpanzee
Pan troglodytes
XP_001165762
794
90647
K71
L
V
Q
E
L
Q
K
K
A
E
H
Q
V
G
E
Rhesus Macaque
Macaca mulatta
XP_001115590
847
94222
S67
T
V
Q
R
L
Q
A
S
A
G
E
Q
G
E
G
Dog
Lupus familis
XP_548092
787
90122
K71
L
V
Q
E
L
Q
K
K
A
E
H
Q
V
G
E
Cat
Felis silvestris
Mouse
Mus musculus
P52633
837
93707
T67
T
V
Q
R
L
Q
A
T
A
G
E
Q
G
K
G
Rat
Rattus norvegicus
Q62771
793
90815
K71
L
V
Q
E
L
Q
K
K
A
E
H
Q
V
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124062
758
86811
L68
L
S
D
Q
M
V
M
L
L
H
Q
V
A
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NAD6
706
80563
H21
T
D
V
S
K
T
C
H
H
L
W
E
E
N
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.6
98.4
38.8
N.A.
84.1
39.2
N.A.
N.A.
N.A.
N.A.
36.1
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
100
55.8
98.9
55.1
N.A.
89.3
56.3
N.A.
N.A.
N.A.
N.A.
54.6
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
100
33.3
86.6
33.3
N.A.
73.3
33.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
33.3
86.6
33.3
N.A.
86.6
33.3
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
38
0
63
0
0
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
13
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
38
0
0
0
0
0
38
38
13
13
25
38
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
38
0
0
38
38
38
% G
% His:
0
0
0
13
0
0
0
13
13
13
38
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
13
0
38
38
0
0
0
0
0
25
13
% K
% Leu:
50
0
0
0
75
0
0
13
13
13
0
0
0
0
0
% L
% Met:
0
0
0
0
13
0
13
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
75
13
0
75
0
0
0
0
13
75
0
0
13
% Q
% Arg:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
13
0
13
0
0
0
25
0
0
0
0
0
0
0
% S
% Thr:
50
0
0
0
0
13
0
13
0
0
0
0
0
0
0
% T
% Val:
0
75
13
0
0
13
0
0
13
0
0
13
38
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _