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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STAT5A All Species: 21.82
Human Site: S726 Identified Species: 48
UniProt: P42229 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42229 NP_003143.2 794 90647 S726 T Y M D Q A P S P A V C P Q A
Chimpanzee Pan troglodytes XP_001165762 794 90647 S726 T Y M D Q A P S P A V C P Q A
Rhesus Macaque Macaca mulatta XP_001109557 794 90645 S726 T Y M D Q A P S P A V C P Q A
Dog Lupus familis XP_548091 794 90625 S726 T Y M D Q A P S P A V C P Q A
Cat Felis silvestris
Mouse Mus musculus P42230 793 90813 S725 T Y M D Q A P S P V V C P Q P
Rat Rattus norvegicus Q62771 793 90815 S725 T Y M D Q A P S P V V C P Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q6DV79 771 88152 N664 Y K I M D A T N I L V S P L V
Frog Xenopus laevis Q7ZXK3 766 87581 N664 Y K I M D A T N I L V S P L V
Zebra Danio Brachydanio rerio NP_919368 785 89465 N714 V P E F A T P N P D P A A N P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24151 761 86396 F693 R D V A F G E F Y S K R Q E P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NAD6 706 80563 P620 F G A D S P S P L S V Q S K L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.6 96.8 N.A. 96.3 95.8 N.A. N.A. 28.9 28.9 77.4 N.A. 31.3 N.A. 24.6 N.A.
Protein Similarity: 100 100 98.9 98.6 N.A. 98.1 97.8 N.A. N.A. 48.3 49.2 87.4 N.A. 48.1 N.A. 43.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. N.A. 20 20 13.3 N.A. 0 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. N.A. 33.3 33.3 20 N.A. 20 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 10 73 0 0 0 37 0 10 10 0 46 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 % C
% Asp: 0 10 0 64 19 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 10 0 0 0 0 0 0 10 0 % E
% Phe: 10 0 0 10 10 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 19 0 0 0 0 0 19 0 0 0 0 0 0 % I
% Lys: 0 19 0 0 0 0 0 0 0 0 10 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 10 19 0 0 0 19 10 % L
% Met: 0 0 55 19 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 28 0 0 0 0 0 10 0 % N
% Pro: 0 10 0 0 0 10 64 10 64 0 10 0 73 0 28 % P
% Gln: 0 0 0 0 55 0 0 0 0 0 0 10 10 55 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 0 10 0 10 55 0 19 0 19 10 0 0 % S
% Thr: 55 0 0 0 0 10 19 0 0 0 0 0 0 0 0 % T
% Val: 10 0 10 0 0 0 0 0 0 19 82 0 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 19 55 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _