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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRIA1 All Species: 22.73
Human Site: T578 Identified Species: 45.45
UniProt: P42261 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42261 NP_000818.2 906 101506 T578 E E G R D Q T T S D Q S N E F
Chimpanzee Pan troglodytes Q5IS46 956 107246 C584 H P C A Q G R C N L L V N Q Y
Rhesus Macaque Macaca mulatta XP_001111076 886 99443 T558 E E G R D Q T T S D Q S N E F
Dog Lupus familis XP_853398 906 101488 T578 E E G R D Q T T S D Q S N E F
Cat Felis silvestris
Mouse Mus musculus P23818 907 101551 T578 E E G R D Q T T S D Q S N E F
Rat Rattus norvegicus P19490 907 101561 T578 E E G R D Q T T S D Q S N E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509706 900 100941 S576 E E G R D Q T S S D Q S N E F
Chicken Gallus gallus P19439 487 54337 F177 E T W T G L L F A Y V L T C V
Frog Xenopus laevis Q91756 479 53388 G168 F S K E T W I G I L V A Y M V
Zebra Danio Brachydanio rerio Q68Y21 1009 113606 P596 W L N P P R L P M G S V S S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q03445 991 111650 P671 S E P Q A H V P P V P P N E F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34299 962 108124 G629 V E E T S R G G F T I S N D F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.2 97.3 99.7 N.A. 97.7 98.5 N.A. 95.3 20.7 21.1 26 N.A. 38.8 N.A. 36.4 N.A.
Protein Similarity: 100 54.7 97.5 99.7 N.A. 98.7 99.3 N.A. 97.4 32.5 34.6 45.8 N.A. 58.3 N.A. 53.7 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 93.3 6.6 0 0 N.A. 26.6 N.A. 26.6 N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 100 13.3 6.6 13.3 N.A. 33.3 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 0 0 0 9 0 0 9 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 9 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 50 0 0 0 0 50 0 0 0 9 0 % D
% Glu: 59 67 9 9 0 0 0 0 0 0 0 0 0 59 0 % E
% Phe: 9 0 0 0 0 0 0 9 9 0 0 0 0 0 67 % F
% Gly: 0 0 50 0 9 9 9 17 0 9 0 0 0 0 0 % G
% His: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 9 0 9 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 0 0 9 17 0 0 17 9 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % M
% Asn: 0 0 9 0 0 0 0 0 9 0 0 0 75 0 0 % N
% Pro: 0 9 9 9 9 0 0 17 9 0 9 9 0 0 0 % P
% Gln: 0 0 0 9 9 50 0 0 0 0 50 0 0 9 0 % Q
% Arg: 0 0 0 50 0 17 9 0 0 0 0 0 0 0 0 % R
% Ser: 9 9 0 0 9 0 0 9 50 0 9 59 9 9 0 % S
% Thr: 0 9 0 17 9 0 50 42 0 9 0 0 9 0 9 % T
% Val: 9 0 0 0 0 0 9 0 0 9 17 17 0 0 17 % V
% Trp: 9 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _