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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SKIV2L2 All Species: 17.58
Human Site: S85 Identified Species: 35.15
UniProt: P42285 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42285 NP_056175.3 1042 117805 S85 K K P R I E E S I T E D L S L
Chimpanzee Pan troglodytes XP_001145794 1042 117753 S85 K K P R I E E S I T E D L S L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849676 1042 117789 S85 K K P R V E E S I T E D L S L
Cat Felis silvestris
Mouse Mus musculus Q9CZU3 1040 117618 S83 K K P R I E D S I N E D L S L
Rat Rattus norvegicus NP_001029265 1042 117927 S85 K K P R I E D S I N E D L S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012962 1029 116029 M83 D N N L A D L M P H V K V Q A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_999933 1034 116547 L83 E E I N L S E L M P K V K S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524929 1055 118907 D97 D E P T R T L D I D D S A T L
Honey Bee Apis mellifera XP_624031 1022 117163 K83 E E L A P R I K I H T I E T I
Nematode Worm Caenorhab. elegans Q23223 1026 116352 I83 E E A R M E N I I V H T I R T
Sea Urchin Strong. purpuratus XP_001180500 1024 116147 H83 I L P Q V K T H D V E C L E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47047 1073 122036 D94 Q E A S R E V D A S K G L T N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 98.8 N.A. 97.5 97.7 N.A. N.A. 91.1 N.A. 85.1 N.A. 62.1 65.3 51.3 73.8
Protein Similarity: 100 99.9 N.A. 99.5 N.A. 99 99.1 N.A. N.A. 94.3 N.A. 91.9 N.A. 76.7 80.2 67.1 86.2
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 86.6 N.A. N.A. 0 N.A. 13.3 N.A. 20 6.6 20 20
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. N.A. 13.3 N.A. 46.6 N.A. 40 33.3 46.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 51.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 70 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 9 9 0 0 0 9 0 0 0 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 17 0 0 0 0 9 17 17 9 9 9 42 0 0 0 % D
% Glu: 25 42 0 0 0 59 34 0 0 0 50 0 9 9 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % G
% His: 0 0 0 0 0 0 0 9 0 17 9 0 0 0 0 % H
% Ile: 9 0 9 0 34 0 9 9 67 0 0 9 9 0 9 % I
% Lys: 42 42 0 0 0 9 0 9 0 0 17 9 9 0 0 % K
% Leu: 0 9 9 9 9 0 17 9 0 0 0 0 59 0 50 % L
% Met: 0 0 0 0 9 0 0 9 9 0 0 0 0 0 0 % M
% Asn: 0 9 9 9 0 0 9 0 0 17 0 0 0 0 9 % N
% Pro: 0 0 59 0 9 0 0 0 9 9 0 0 0 0 0 % P
% Gln: 9 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 0 0 0 50 17 9 0 0 0 0 0 0 0 9 0 % R
% Ser: 0 0 0 9 0 9 0 42 0 9 0 9 0 50 0 % S
% Thr: 0 0 0 9 0 9 9 0 0 25 9 9 0 25 9 % T
% Val: 0 0 0 0 17 0 9 0 0 17 9 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _