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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SKIV2L2 All Species: 48.18
Human Site: T499 Identified Species: 96.36
UniProt: P42285 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42285 NP_056175.3 1042 117805 T499 P A R T V L F T N A R K F D G
Chimpanzee Pan troglodytes XP_001145794 1042 117753 T499 P A R T V L F T N A R K F D G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849676 1042 117789 T499 P A R T V L F T N A R K F D G
Cat Felis silvestris
Mouse Mus musculus Q9CZU3 1040 117618 T497 P A R T V L F T N A R K Y D G
Rat Rattus norvegicus NP_001029265 1042 117927 T499 P A R T V L F T N A R K Y D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012962 1029 116029 T486 P A R T V L F T S A S K F D G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_999933 1034 116547 T492 P A R T V L F T S A R K F D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524929 1055 118907 T515 P A R T V L F T A P R K F D G
Honey Bee Apis mellifera XP_624031 1022 117163 T485 P A R T V L F T A S R K F D G
Nematode Worm Caenorhab. elegans Q23223 1026 116352 T486 P A R T V V F T S A R K F D G
Sea Urchin Strong. purpuratus XP_001180500 1024 116147 T480 P A R T V I F T N P R K F D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47047 1073 122036 T519 P A K T V V F T S V R K W D G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 98.8 N.A. 97.5 97.7 N.A. N.A. 91.1 N.A. 85.1 N.A. 62.1 65.3 51.3 73.8
Protein Similarity: 100 99.9 N.A. 99.5 N.A. 99 99.1 N.A. N.A. 94.3 N.A. 91.9 N.A. 76.7 80.2 67.1 86.2
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 93.3 N.A. 86.6 86.6 86.6 86.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 93.3 N.A. 100 N.A. 86.6 93.3 100 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 51.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 70 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 100 0 0 0 0 0 0 17 67 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 100 0 0 0 0 0 75 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 0 0 0 100 0 0 0 % K
% Leu: 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % N
% Pro: 100 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 92 0 0 0 0 0 0 0 92 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 34 9 9 0 0 0 0 % S
% Thr: 0 0 0 100 0 0 0 100 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 100 17 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _