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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKIV2L2
All Species:
23.33
Human Site:
Y122
Identified Species:
46.67
UniProt:
P42285
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42285
NP_056175.3
1042
117805
Y122
A
L
P
A
E
E
D
Y
L
P
L
K
P
R
V
Chimpanzee
Pan troglodytes
XP_001145794
1042
117753
Y122
A
L
P
A
D
E
D
Y
L
P
L
K
P
R
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849676
1042
117789
Y122
A
L
P
A
D
E
D
Y
L
P
L
K
P
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZU3
1040
117618
Y120
A
L
P
A
D
E
D
Y
I
P
L
K
P
R
V
Rat
Rattus norvegicus
NP_001029265
1042
117927
Y122
A
L
P
A
D
E
D
Y
I
P
L
K
P
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012962
1029
116029
A120
K
P
R
T
G
K
P
A
K
E
Y
P
F
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999933
1034
116547
A120
L
K
P
R
V
G
K
A
A
K
E
Y
P
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524929
1055
118907
Y134
A
A
H
P
D
Q
E
Y
I
P
L
K
P
F
S
Honey Bee
Apis mellifera
XP_624031
1022
117163
K120
S
K
P
A
K
E
Y
K
F
V
L
D
P
F
Q
Nematode Worm
Caenorhab. elegans
Q23223
1026
116352
K120
N
S
G
T
E
P
A
K
Y
Y
P
F
Q
L
D
Sea Urchin
Strong. purpuratus
XP_001180500
1024
116147
I120
A
A
K
D
Y
P
F
I
L
D
P
F
Q
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47047
1073
122036
Y131
A
L
P
P
N
Y
D
Y
T
P
I
A
E
H
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98.8
N.A.
97.5
97.7
N.A.
N.A.
91.1
N.A.
85.1
N.A.
62.1
65.3
51.3
73.8
Protein Similarity:
100
99.9
N.A.
99.5
N.A.
99
99.1
N.A.
N.A.
94.3
N.A.
91.9
N.A.
76.7
80.2
67.1
86.2
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
86.6
86.6
N.A.
N.A.
0
N.A.
13.3
N.A.
40
33.3
6.6
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
20
N.A.
66.6
46.6
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
51.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
70
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
17
0
50
0
0
9
17
9
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
42
0
50
0
0
9
0
9
0
0
9
% D
% Glu:
0
0
0
0
17
50
9
0
0
9
9
0
9
0
9
% E
% Phe:
0
0
0
0
0
0
9
0
9
0
0
17
9
25
0
% F
% Gly:
0
0
9
0
9
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
9
25
0
9
0
0
0
9
% I
% Lys:
9
17
9
0
9
9
9
17
9
9
0
50
0
9
9
% K
% Leu:
9
50
0
0
0
0
0
0
34
0
59
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
67
17
0
17
9
0
0
59
17
9
67
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
17
0
9
% Q
% Arg:
0
0
9
9
0
0
0
0
0
0
0
0
0
42
0
% R
% Ser:
9
9
0
0
0
0
0
0
0
0
0
0
0
9
9
% S
% Thr:
0
0
0
17
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
42
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
9
9
59
9
9
9
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _