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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SKIV2L2 All Species: 36.06
Human Site: Y311 Identified Species: 72.12
UniProt: P42285 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42285 NP_056175.3 1042 117805 Y311 C H V I Y T D Y R P T P L Q H
Chimpanzee Pan troglodytes XP_001145794 1042 117753 Y311 C H V I Y T D Y R P T P L Q H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849676 1042 117789 Y311 C H V I Y T D Y R P T P L Q H
Cat Felis silvestris
Mouse Mus musculus Q9CZU3 1040 117618 Y309 C H V I Y T D Y R P T P L Q H
Rat Rattus norvegicus NP_001029265 1042 117927 Y311 C H V I Y T D Y R P T P L Q H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012962 1029 116029 Y298 C H V I Y T D Y R P T P L Q H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_999933 1034 116547 Y299 C H V V Y T D Y R P T P L Q H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524929 1055 118907 Y323 C H V V Y T D Y R P T P L Q H
Honey Bee Apis mellifera XP_624031 1022 117163 F304 T P L Q H Y I F P V G G D G I
Nematode Worm Caenorhab. elegans Q23223 1026 116352 Y297 V N V V Y T D Y R P T P L Q H
Sea Urchin Strong. purpuratus XP_001180500 1024 116147 F302 V P L Q H Y I F P A G G D G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47047 1073 122036 F321 C H I V Y T N F R P T P L Q H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 98.8 N.A. 97.5 97.7 N.A. N.A. 91.1 N.A. 85.1 N.A. 62.1 65.3 51.3 73.8
Protein Similarity: 100 99.9 N.A. 99.5 N.A. 99 99.1 N.A. N.A. 94.3 N.A. 91.9 N.A. 76.7 80.2 67.1 86.2
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 N.A. 93.3 N.A. 93.3 0 80 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 100 20 93.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 51.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 70 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 75 0 0 0 0 0 17 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 17 17 0 17 0 % G
% His: 0 75 0 0 17 0 0 0 0 0 0 0 0 0 84 % H
% Ile: 0 0 9 50 0 0 17 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 17 0 0 0 0 0 0 0 0 0 84 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 17 0 0 0 0 0 0 17 84 0 84 0 0 0 % P
% Gln: 0 0 0 17 0 0 0 0 0 0 0 0 0 84 0 % Q
% Arg: 0 0 0 0 0 0 0 0 84 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 9 0 0 0 0 84 0 0 0 0 84 0 0 0 0 % T
% Val: 17 0 75 34 0 0 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 84 17 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _