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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP25
All Species:
16.67
Human Site:
S545
Identified Species:
52.38
UniProt:
P42331
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42331
NP_001007232.1
645
73435
S545
T
G
P
G
K
K
N
S
G
E
E
E
I
D
S
Chimpanzee
Pan troglodytes
XP_001135470
646
73502
S546
T
G
P
G
K
K
N
S
G
E
E
E
I
D
S
Rhesus Macaque
Macaca mulatta
XP_001095743
646
73554
S546
T
G
P
G
K
K
N
S
G
E
E
E
L
D
S
Dog
Lupus familis
XP_538527
713
78537
S613
T
G
P
E
K
K
N
S
G
E
E
K
L
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYW1
648
73364
S546
M
E
A
G
S
K
N
S
G
E
D
D
L
D
S
Rat
Rattus norvegicus
Q5U2Z7
748
84125
N636
N
S
E
T
F
V
G
N
T
S
S
N
H
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026054
650
73116
P549
S
P
S
E
V
F
Q
P
A
S
E
S
K
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690970
695
77458
D590
D
K
G
N
V
T
E
D
N
D
T
S
T
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.1
69.5
N.A.
86.8
38
N.A.
N.A.
61.8
N.A.
38.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
98.4
76.4
N.A.
91.3
54.4
N.A.
N.A.
73.8
N.A.
58.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
53.3
0
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
13.3
N.A.
N.A.
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
13
0
0
0
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
0
0
13
0
13
13
13
0
50
0
% D
% Glu:
0
13
13
25
0
0
13
0
0
63
63
38
0
25
0
% E
% Phe:
0
0
0
0
13
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
13
50
0
0
13
0
63
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% I
% Lys:
0
13
0
0
50
63
0
0
0
0
0
13
13
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
0
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
13
0
0
63
13
13
0
0
13
0
0
0
% N
% Pro:
0
13
50
0
0
0
0
13
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
13
13
0
13
0
0
63
0
25
13
25
0
13
75
% S
% Thr:
50
0
0
13
0
13
0
0
13
0
13
0
13
13
0
% T
% Val:
0
0
0
0
25
13
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _