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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIK3CB
All Species:
25.25
Human Site:
S1070
Identified Species:
39.68
UniProt:
P42338
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42338
NP_006210.1
1070
122762
S1070
T
V
R
K
D
Y
R
S
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001160550
1044
119347
Q1044
N
V
S
K
D
N
R
Q
_
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001113960
1070
122801
S1070
T
V
R
K
D
Y
R
S
_
_
_
_
_
_
_
Dog
Lupus familis
XP_534280
1070
122787
S1070
T
V
R
K
D
Y
R
S
_
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTI9
1064
121735
S1064
T
V
R
K
D
Y
R
S
_
_
_
_
_
_
_
Rat
Rattus norvegicus
Q9Z1L0
1070
122589
S1070
T
V
R
K
D
Y
R
S
_
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516423
1162
131381
Chicken
Gallus gallus
NP_001026482
1066
122000
S1066
T
V
R
K
D
Y
R
S
_
_
_
_
_
_
_
Frog
Xenopus laevis
Q6AZN6
886
101139
Zebra Danio
Brachydanio rerio
XP_001923257
1022
117051
H1020
W
M
A
H
I
V
A
H
P
S
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623897
1071
123316
T1070
N
M
S
K
N
N
K
T
T
_
_
_
_
_
_
Nematode Worm
Caenorhab. elegans
Q94125
1182
136855
H1181
W
L
F
H
A
V
K
H
Y
_
_
_
_
_
_
Sea Urchin
Strong. purpuratus
XP_001201471
1049
120959
D1049
M
H
H
I
A
H
R
D
_
_
_
_
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42339
814
93309
Baker's Yeast
Sacchar. cerevisiae
P22543
875
100903
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.5
99.6
97.2
N.A.
95.2
95.8
N.A.
81.1
86.6
23.6
65.5
N.A.
N.A.
46.6
26.4
42.9
Protein Similarity:
100
72.9
99.9
98.8
N.A.
97
97.8
N.A.
85.3
93.6
41.3
79.7
N.A.
N.A.
65.6
47.8
63.6
P-Site Identity:
100
50
100
100
N.A.
100
100
N.A.
0
100
0
0
N.A.
N.A.
11.1
0
12.5
P-Site Similarity:
100
50
100
100
N.A.
100
100
N.A.
0
100
0
10
N.A.
N.A.
55.5
33.3
25
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
14
0
7
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
47
0
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
7
14
0
7
0
14
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
54
0
0
14
0
0
0
0
0
0
0
0
% K
% Leu:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
7
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
0
0
0
7
14
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
40
0
0
0
54
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
14
0
0
0
0
40
0
7
0
0
0
0
0
% S
% Thr:
40
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% T
% Val:
0
47
0
0
0
14
0
0
0
0
0
0
0
0
0
% V
% Trp:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
40
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
54
67
74
74
74
74
74
% _