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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRAP1
All Species:
14.24
Human Site:
S27
Identified Species:
31.33
UniProt:
P42345
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42345
NP_004949.1
2549
288892
S27
S
V
L
Q
Q
F
A
S
G
L
K
S
R
N
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535407
2550
288910
S27
S
V
L
Q
Q
F
A
S
G
L
K
S
R
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLN9
2549
288718
S27
S
V
L
Q
Q
F
A
S
G
L
K
S
R
N
E
Rat
Rattus norvegicus
P42346
2549
288776
S27
S
V
L
Q
Q
F
A
S
G
L
K
S
R
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510680
2493
282092
A27
F
G
S
G
W
W
E
A
G
T
F
R
F
R
S
Chicken
Gallus gallus
XP_417614
2463
280042
E29
L
P
S
L
I
G
V
E
G
G
N
A
T
R
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070679
2515
286136
D29
T
R
A
K
A
A
K
D
L
Q
H
Y
V
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VK45
2470
281015
Y32
A
T
Q
D
L
L
F
Y
V
K
T
E
L
R
E
Honey Bee
Apis mellifera
XP_625130
2442
278856
D27
I
R
N
K
A
A
R
D
L
C
L
Y
V
K
T
Nematode Worm
Caenorhab. elegans
Q95Q95
2697
306510
N65
I
T
E
N
R
D
A
N
Q
R
Q
A
A
R
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32600
2474
281549
K94
N
L
I
F
D
K
L
K
S
D
V
P
Q
E
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.4
N.A.
98.9
98.9
N.A.
88.8
93.7
N.A.
89.8
N.A.
54
62
34.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.5
N.A.
99.2
99.2
N.A.
91.2
95.4
N.A.
94.5
N.A.
69.8
75.7
53.4
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
6.6
N.A.
0
N.A.
6.6
0
13.3
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
20
13.3
N.A.
13.3
N.A.
13.3
6.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
19
19
46
10
0
0
0
19
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
10
0
19
0
10
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
10
10
0
0
0
10
0
10
55
% E
% Phe:
10
0
0
10
0
37
10
0
0
0
10
0
10
0
0
% F
% Gly:
0
10
0
10
0
10
0
0
55
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
19
0
10
0
10
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
19
0
10
10
10
0
10
37
0
0
10
0
% K
% Leu:
10
10
37
10
10
10
10
0
19
37
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
10
0
0
0
10
0
0
10
0
0
37
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
10
37
37
0
0
0
10
10
10
0
10
0
0
% Q
% Arg:
0
19
0
0
10
0
10
0
0
10
0
10
37
37
10
% R
% Ser:
37
0
19
0
0
0
0
37
10
0
0
37
0
0
10
% S
% Thr:
10
19
0
0
0
0
0
0
0
10
10
0
10
10
19
% T
% Val:
0
37
0
0
0
0
10
0
10
0
10
0
19
0
0
% V
% Trp:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _