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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRAP1
All Species:
19.7
Human Site:
S386
Identified Species:
43.33
UniProt:
P42345
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42345
NP_004949.1
2549
288892
S386
K
C
R
N
S
K
N
S
L
I
Q
M
T
I
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535407
2550
288910
S386
K
C
R
N
S
K
N
S
L
I
Q
M
T
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLN9
2549
288718
S386
K
C
R
S
S
K
N
S
L
I
Q
M
T
I
L
Rat
Rattus norvegicus
P42346
2549
288776
S386
K
C
R
S
S
K
N
S
L
I
Q
M
T
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510680
2493
282092
S344
K
C
R
N
S
K
N
S
L
I
Q
M
T
I
L
Chicken
Gallus gallus
XP_417614
2463
280042
A332
L
N
L
L
P
R
L
A
A
F
R
P
S
A
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070679
2515
286136
N371
L
K
Y
R
T
S
K
N
P
L
I
Q
M
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VK45
2470
281015
P371
E
Q
R
T
S
K
S
P
Y
V
Q
Q
A
L
L
Honey Bee
Apis mellifera
XP_625130
2442
278856
P349
N
Q
R
I
S
R
N
P
H
I
Q
H
A
L
M
Nematode Worm
Caenorhab. elegans
Q95Q95
2697
306510
I411
L
M
Q
L
L
P
R
I
C
A
F
P
Q
C
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32600
2474
281549
Y397
L
D
R
I
M
V
H
Y
L
R
Y
L
K
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.4
N.A.
98.9
98.9
N.A.
88.8
93.7
N.A.
89.8
N.A.
54
62
34.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.5
N.A.
99.2
99.2
N.A.
91.2
95.4
N.A.
94.5
N.A.
69.8
75.7
53.4
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
100
0
N.A.
0
N.A.
33.3
33.3
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
26.6
N.A.
26.6
N.A.
60
53.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
10
0
0
19
10
0
% A
% Cys:
0
46
0
0
0
0
0
0
10
0
0
0
0
10
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
10
0
0
10
0
0
0
% H
% Ile:
0
0
0
19
0
0
0
10
0
55
10
0
0
46
19
% I
% Lys:
46
10
0
0
0
55
10
0
0
0
0
0
10
0
0
% K
% Leu:
37
0
10
19
10
0
10
0
55
10
0
10
0
19
55
% L
% Met:
0
10
0
0
10
0
0
0
0
0
0
46
10
0
10
% M
% Asn:
10
10
0
28
0
0
55
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
10
10
0
19
10
0
0
19
0
0
0
% P
% Gln:
0
19
10
0
0
0
0
0
0
0
64
19
10
0
0
% Q
% Arg:
0
0
73
10
0
19
10
0
0
10
10
0
0
0
0
% R
% Ser:
0
0
0
19
64
10
10
46
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
10
10
0
0
0
0
0
0
0
46
10
0
% T
% Val:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
10
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _