KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRAP1
All Species:
18.79
Human Site:
T220
Identified Species:
41.33
UniProt:
P42345
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42345
NP_004949.1
2549
288892
T220
L
R
A
C
L
I
L
T
T
Q
R
E
P
K
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535407
2550
288910
T220
L
R
A
C
L
I
L
T
T
Q
R
E
P
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLN9
2549
288718
T220
L
R
A
C
L
I
L
T
T
Q
R
E
P
K
E
Rat
Rattus norvegicus
P42346
2549
288776
T220
L
R
A
C
L
I
L
T
T
Q
R
E
P
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510680
2493
282092
C178
S
S
L
P
G
G
G
C
G
M
E
L
D
E
A
Chicken
Gallus gallus
XP_417614
2463
280042
T180
A
E
K
G
F
D
E
T
L
A
K
E
K
G
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070679
2515
286136
T206
L
R
A
C
L
I
L
T
T
Q
R
E
T
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VK45
2470
281015
A208
R
A
A
L
I
V
T
A
Q
R
E
S
T
K
Q
Honey Bee
Apis mellifera
XP_625130
2442
278856
R199
E
G
A
V
E
A
L
R
A
A
L
V
V
T
A
Nematode Worm
Caenorhab. elegans
Q95Q95
2697
306510
D261
A
V
R
I
A
G
I
D
A
L
H
V
V
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32600
2474
281549
I247
R
H
A
A
L
L
I
I
K
A
L
A
D
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.4
N.A.
98.9
98.9
N.A.
88.8
93.7
N.A.
89.8
N.A.
54
62
34.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.5
N.A.
99.2
99.2
N.A.
91.2
95.4
N.A.
94.5
N.A.
69.8
75.7
53.4
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
13.3
N.A.
93.3
N.A.
13.3
13.3
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
20
N.A.
93.3
N.A.
40
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
73
10
10
10
0
10
19
28
0
10
0
0
19
% A
% Cys:
0
0
0
46
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
0
0
0
0
19
0
0
% D
% Glu:
10
10
0
0
10
0
10
0
0
0
19
55
0
10
46
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
10
19
10
0
10
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
10
10
46
19
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
10
0
10
0
10
55
0
% K
% Leu:
46
0
10
10
55
10
55
0
10
10
19
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
37
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
46
0
0
0
0
10
% Q
% Arg:
19
46
10
0
0
0
0
10
0
10
46
0
0
0
0
% R
% Ser:
10
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% S
% Thr:
0
0
0
0
0
0
10
55
46
0
0
0
19
10
10
% T
% Val:
0
10
0
10
0
10
0
0
0
0
0
19
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _