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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRAP1
All Species:
31.52
Human Site:
Y853
Identified Species:
69.33
UniProt:
P42345
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42345
NP_004949.1
2549
288892
Y853
Q
L
V
A
S
T
G
Y
V
V
E
P
Y
R
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535407
2550
288910
Y853
Q
L
V
A
S
T
G
Y
V
V
E
P
Y
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLN9
2549
288718
Y853
Q
L
V
A
S
T
G
Y
V
V
E
P
Y
R
K
Rat
Rattus norvegicus
P42346
2549
288776
Y853
Q
L
V
A
S
T
G
Y
V
V
E
P
Y
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510680
2493
282092
Y811
Q
L
V
A
S
T
G
Y
V
V
E
P
Y
R
K
Chicken
Gallus gallus
XP_417614
2463
280042
Y785
Q
L
V
A
S
T
G
Y
V
V
E
P
Y
R
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070679
2515
286136
Y836
Q
Q
V
A
S
T
G
Y
V
V
E
P
Y
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VK45
2470
281015
R829
Q
L
I
S
A
T
G
R
V
V
T
P
Y
H
K
Honey Bee
Apis mellifera
XP_625130
2442
278856
H801
Q
L
V
G
S
T
G
H
V
V
K
P
Y
M
Q
Nematode Worm
Caenorhab. elegans
Q95Q95
2697
306510
Y853
G
I
C
R
S
T
A
Y
V
V
D
P
Y
R
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32600
2474
281549
T825
K
R
D
A
A
L
T
T
L
G
Q
L
A
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.4
N.A.
98.9
98.9
N.A.
88.8
93.7
N.A.
89.8
N.A.
54
62
34.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.5
N.A.
99.2
99.2
N.A.
91.2
95.4
N.A.
94.5
N.A.
69.8
75.7
53.4
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
60
66.6
53.3
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
80
86.6
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
73
19
0
10
0
0
0
0
0
10
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
64
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
82
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
73
% K
% Leu:
0
73
0
0
0
10
0
0
10
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% P
% Gln:
82
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% Q
% Arg:
0
10
0
10
0
0
0
10
0
0
0
0
0
73
0
% R
% Ser:
0
0
0
10
82
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
91
10
10
0
0
10
0
0
0
0
% T
% Val:
0
0
73
0
0
0
0
0
91
91
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
0
91
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _