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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAL
All Species:
34.85
Human Site:
S155
Identified Species:
69.7
UniProt:
P42357
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42357
NP_002099.1
657
72698
S155
K
S
R
E
V
I
D
S
I
I
K
E
K
T
V
Chimpanzee
Pan troglodytes
XP_509282
657
72684
S155
K
S
R
E
V
I
D
S
I
I
K
E
K
T
V
Rhesus Macaque
Macaca mulatta
XP_001107685
657
72546
S155
K
S
R
E
V
I
D
S
I
I
E
E
K
T
V
Dog
Lupus familis
XP_532657
657
72129
S155
K
S
R
E
V
I
E
S
I
V
K
E
K
T
V
Cat
Felis silvestris
Mouse
Mus musculus
P35492
657
72239
S155
Q
S
R
E
V
I
D
S
I
I
K
E
R
T
V
Rat
Rattus norvegicus
P21213
657
72265
S155
Q
S
R
E
V
I
D
S
I
I
K
E
R
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511071
660
72931
S155
Q
S
R
D
V
I
E
S
I
V
K
E
Q
T
V
Chicken
Gallus gallus
NP_989735
660
72944
R155
Q
S
R
E
V
I
E
R
I
V
K
E
Q
T
V
Frog
Xenopus laevis
NP_001086064
664
73188
S155
Q
S
R
L
L
I
D
S
I
V
Q
E
N
K
V
Zebra Danio
Brachydanio rerio
NP_001082926
654
72108
T155
E
S
R
E
L
L
D
T
I
V
K
E
N
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20502
677
74616
K171
K
A
R
T
F
L
E
K
I
A
S
E
H
R
A
Sea Urchin
Strong. purpuratus
XP_788713
658
72544
N151
K
A
R
E
L
V
D
N
I
L
K
E
N
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.5
94.9
N.A.
93.7
93.9
N.A.
90
87.5
84.3
80.2
N.A.
N.A.
N.A.
52.8
63.2
Protein Similarity:
100
99.5
98.7
97.8
N.A.
97.2
97.4
N.A.
95.7
93.3
92.4
88.8
N.A.
N.A.
N.A.
68.6
76.7
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
66.6
66.6
53.3
53.3
N.A.
N.A.
N.A.
26.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
80
86.6
N.A.
N.A.
N.A.
46.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
0
0
0
0
9
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
67
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
75
0
0
34
0
0
0
9
100
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
75
0
0
100
42
0
0
0
0
0
% I
% Lys:
50
0
0
0
0
0
0
9
0
0
75
0
34
25
0
% K
% Leu:
0
0
0
9
25
17
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
25
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
42
0
0
0
0
0
0
0
0
0
9
0
17
0
0
% Q
% Arg:
0
0
100
0
0
0
0
9
0
0
0
0
17
9
0
% R
% Ser:
0
84
0
0
0
0
0
67
0
0
9
0
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
9
0
0
0
0
0
67
0
% T
% Val:
0
0
0
0
67
9
0
0
0
42
0
0
0
0
92
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _