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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAL All Species: 39.7
Human Site: S631 Identified Species: 79.39
UniProt: P42357 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42357 NP_002099.1 657 72698 S631 R M E H I P E S R P L S P T A
Chimpanzee Pan troglodytes XP_509282 657 72684 S631 R M E H I P E S R P L S P T A
Rhesus Macaque Macaca mulatta XP_001107685 657 72546 S631 R M E H I P E S R P L S P T A
Dog Lupus familis XP_532657 657 72129 S631 R M E H I P E S R P V S P T A
Cat Felis silvestris
Mouse Mus musculus P35492 657 72239 S631 R M E H I P E S R P L S P T A
Rat Rattus norvegicus P21213 657 72265 S631 R M E H I P E S R P L S P T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511071 660 72931 S631 R R E H I P E S R P I S P T A
Chicken Gallus gallus NP_989735 660 72944 S631 R R E H I P E S R P G S P T A
Frog Xenopus laevis NP_001086064 664 73188 S631 R M E H I P E S R P S S P T S
Zebra Danio Brachydanio rerio NP_001082926 654 72108 Y627 I E K Y C M E Y I P E S R P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20502 677 74616 P647 E A M E E L D P D A L R Q F T
Sea Urchin Strong. purpuratus XP_788713 658 72544 T627 E S E Q L K E T K V H S P T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 97.5 94.9 N.A. 93.7 93.9 N.A. 90 87.5 84.3 80.2 N.A. N.A. N.A. 52.8 63.2
Protein Similarity: 100 99.5 98.7 97.8 N.A. 97.2 97.4 N.A. 95.7 93.3 92.4 88.8 N.A. N.A. N.A. 68.6 76.7
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 86.6 86.6 86.6 20 N.A. N.A. N.A. 6.6 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 86.6 93.3 40 N.A. N.A. N.A. 13.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 67 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 9 0 0 0 0 0 0 % D
% Glu: 17 9 84 9 9 0 92 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 75 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 9 0 0 0 75 0 0 0 9 0 9 0 0 0 0 % I
% Lys: 0 0 9 0 0 9 0 0 9 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 9 9 0 0 0 0 50 0 0 0 0 % L
% Met: 0 59 9 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 75 0 9 0 84 0 0 84 9 0 % P
% Gln: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % Q
% Arg: 75 17 0 0 0 0 0 0 75 0 0 9 9 0 0 % R
% Ser: 0 9 0 0 0 0 0 75 0 0 9 92 0 0 25 % S
% Thr: 0 0 0 0 0 0 0 9 0 0 0 0 0 84 9 % T
% Val: 0 0 0 0 0 0 0 0 0 9 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _