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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAL
All Species:
39.09
Human Site:
S635
Identified Species:
78.18
UniProt:
P42357
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42357
NP_002099.1
657
72698
S635
I
P
E
S
R
P
L
S
P
T
A
F
S
L
Q
Chimpanzee
Pan troglodytes
XP_509282
657
72684
S635
I
P
E
S
R
P
L
S
P
T
A
F
S
L
Q
Rhesus Macaque
Macaca mulatta
XP_001107685
657
72546
S635
I
P
E
S
R
P
L
S
P
T
A
F
S
L
K
Dog
Lupus familis
XP_532657
657
72129
S635
I
P
E
S
R
P
V
S
P
T
A
F
S
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P35492
657
72239
S635
I
P
E
S
R
P
L
S
P
T
A
F
S
L
E
Rat
Rattus norvegicus
P21213
657
72265
S635
I
P
E
S
R
P
L
S
P
T
A
F
S
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511071
660
72931
S635
I
P
E
S
R
P
I
S
P
T
A
F
T
L
A
Chicken
Gallus gallus
NP_989735
660
72944
S635
I
P
E
S
R
P
G
S
P
T
A
F
S
L
G
Frog
Xenopus laevis
NP_001086064
664
73188
S635
I
P
E
S
R
P
S
S
P
T
S
F
S
M
E
Zebra Danio
Brachydanio rerio
NP_001082926
654
72108
S631
C
M
E
Y
I
P
E
S
R
P
S
S
P
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20502
677
74616
R651
E
L
D
P
D
A
L
R
Q
F
T
K
T
P
T
Sea Urchin
Strong. purpuratus
XP_788713
658
72544
S631
L
K
E
T
K
V
H
S
P
T
S
S
V
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.5
94.9
N.A.
93.7
93.9
N.A.
90
87.5
84.3
80.2
N.A.
N.A.
N.A.
52.8
63.2
Protein Similarity:
100
99.5
98.7
97.8
N.A.
97.2
97.4
N.A.
95.7
93.3
92.4
88.8
N.A.
N.A.
N.A.
68.6
76.7
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
80
86.6
73.3
20
N.A.
N.A.
N.A.
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
93.3
26.6
N.A.
N.A.
N.A.
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
67
0
0
0
17
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
92
0
0
0
9
0
0
0
0
0
0
0
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
75
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
17
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
75
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
9
0
0
0
0
0
0
9
0
0
9
% K
% Leu:
9
9
0
0
0
0
50
0
0
0
0
0
0
75
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
75
0
9
0
84
0
0
84
9
0
0
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
17
% Q
% Arg:
0
0
0
0
75
0
0
9
9
0
0
0
0
0
0
% R
% Ser:
0
0
0
75
0
0
9
92
0
0
25
17
67
0
0
% S
% Thr:
0
0
0
9
0
0
0
0
0
84
9
0
17
9
9
% T
% Val:
0
0
0
0
0
9
9
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _