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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAL
All Species:
22.73
Human Site:
S648
Identified Species:
45.45
UniProt:
P42357
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42357
NP_002099.1
657
72698
S648
L
Q
F
L
H
K
K
S
T
K
I
P
E
S
E
Chimpanzee
Pan troglodytes
XP_509282
657
72684
S648
L
Q
F
L
H
K
K
S
T
K
I
P
E
S
E
Rhesus Macaque
Macaca mulatta
XP_001107685
657
72546
S648
L
K
F
L
H
K
K
S
T
K
I
P
E
T
E
Dog
Lupus familis
XP_532657
657
72129
S648
L
E
F
L
H
K
K
S
T
K
I
P
E
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P35492
657
72239
S648
L
E
S
L
R
K
N
S
A
T
I
P
E
S
D
Rat
Rattus norvegicus
P21213
657
72265
S648
L
E
S
L
R
K
N
S
A
T
I
P
E
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511071
660
72931
T648
L
A
S
L
H
I
K
T
N
A
K
Q
D
L
P
Chicken
Gallus gallus
NP_989735
660
72944
T648
L
G
S
L
E
R
K
T
H
D
G
H
N
H
R
Frog
Xenopus laevis
NP_001086064
664
73188
N648
M
E
S
S
S
L
N
N
S
C
S
H
D
P
S
Zebra Danio
Brachydanio rerio
NP_001082926
654
72108
P644
T
A
F
A
L
D
P
P
P
S
P
R
K
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20502
677
74616
R664
P
T
G
I
V
Q
D
R
S
M
I
P
I
S
D
Sea Urchin
Strong. purpuratus
XP_788713
658
72544
N644
L
G
T
T
T
R
S
N
K
R
K
R
T
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.5
94.9
N.A.
93.7
93.9
N.A.
90
87.5
84.3
80.2
N.A.
N.A.
N.A.
52.8
63.2
Protein Similarity:
100
99.5
98.7
97.8
N.A.
97.2
97.4
N.A.
95.7
93.3
92.4
88.8
N.A.
N.A.
N.A.
68.6
76.7
P-Site Identity:
100
100
86.6
86.6
N.A.
53.3
53.3
N.A.
26.6
20
0
6.6
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
66.6
66.6
N.A.
40
33.3
33.3
13.3
N.A.
N.A.
N.A.
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
9
0
0
0
0
17
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
9
0
0
9
0
0
17
0
25
% D
% Glu:
0
34
0
0
9
0
0
0
0
0
0
0
50
0
25
% E
% Phe:
0
0
42
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
17
9
0
0
0
0
0
0
0
9
0
0
0
9
% G
% His:
0
0
0
0
42
0
0
0
9
0
0
17
0
9
0
% H
% Ile:
0
0
0
9
0
9
0
0
0
0
59
0
9
0
0
% I
% Lys:
0
9
0
0
0
50
50
0
9
34
17
0
9
9
0
% K
% Leu:
75
0
0
67
9
9
0
0
0
0
0
0
0
9
0
% L
% Met:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
25
17
9
0
0
0
9
0
0
% N
% Pro:
9
0
0
0
0
0
9
9
9
0
9
59
0
9
9
% P
% Gln:
0
17
0
0
0
9
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
17
17
0
9
0
9
0
17
0
9
9
% R
% Ser:
0
0
42
9
9
0
9
50
17
9
9
0
0
50
17
% S
% Thr:
9
9
9
9
9
0
0
17
34
17
0
0
9
9
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _