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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAL All Species: 40
Human Site: S96 Identified Species: 80
UniProt: P42357 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42357 NP_002099.1 657 72698 S96 M S P D F I P S Q P E G V Y L
Chimpanzee Pan troglodytes XP_509282 657 72684 S96 M S P D F I P S Q P E G V Y L
Rhesus Macaque Macaca mulatta XP_001107685 657 72546 S96 M S P D F I P S Q P E G V Y L
Dog Lupus familis XP_532657 657 72129 S96 M S P D F I P S Q P E G V Y L
Cat Felis silvestris
Mouse Mus musculus P35492 657 72239 S96 M S P D F I P S Q P E G V F L
Rat Rattus norvegicus P21213 657 72265 S96 M S P D F I P S Q P E G V F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511071 660 72931 S96 M S P D F I P S Q P E G V Y L
Chicken Gallus gallus NP_989735 660 72944 S96 M S P D F I P S Q P E G V H L
Frog Xenopus laevis NP_001086064 664 73188 S96 M S P D F I P S Q P E G V H L
Zebra Danio Brachydanio rerio NP_001082926 654 72108 S96 M S Q D F I P S Q P A T S H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20502 677 74616 V112 I D N R R R K V S F A D S L A
Sea Urchin Strong. purpuratus XP_788713 658 72544 S92 Q Q D I M D F S P G S P Q I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 97.5 94.9 N.A. 93.7 93.9 N.A. 90 87.5 84.3 80.2 N.A. N.A. N.A. 52.8 63.2
Protein Similarity: 100 99.5 98.7 97.8 N.A. 97.2 97.4 N.A. 95.7 93.3 92.4 88.8 N.A. N.A. N.A. 68.6 76.7
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 93.3 93.3 66.6 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 73.3 N.A. N.A. N.A. 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 9 84 0 9 0 0 0 0 0 9 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 % E
% Phe: 0 0 0 0 84 0 9 0 0 9 0 0 0 17 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 9 0 75 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % H
% Ile: 9 0 0 9 0 84 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 84 % L
% Met: 84 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 75 0 0 0 84 0 9 84 0 9 0 0 0 % P
% Gln: 9 9 9 0 0 0 0 0 84 0 0 0 9 0 0 % Q
% Arg: 0 0 0 9 9 9 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 84 0 0 0 0 0 92 9 0 9 0 17 0 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 0 0 0 0 75 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 42 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _