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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLLT3
All Species:
32.12
Human Site:
S374
Identified Species:
64.24
UniProt:
P42568
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42568
NP_004520.2
568
63351
S374
E
E
N
I
S
S
K
S
D
S
E
Q
P
S
P
Chimpanzee
Pan troglodytes
XP_001148491
567
63262
S373
E
E
N
I
S
S
K
S
D
S
E
Q
P
S
P
Rhesus Macaque
Macaca mulatta
XP_001108646
570
63507
S376
E
E
N
I
S
S
K
S
D
S
E
Q
P
S
P
Dog
Lupus familis
XP_538677
568
63352
S374
E
E
N
M
S
S
K
S
D
S
E
Q
P
S
P
Cat
Felis silvestris
Mouse
Mus musculus
A2AM29
569
63357
S375
E
E
N
M
S
S
K
S
D
S
E
Q
P
S
P
Rat
Rattus norvegicus
NP_446170
370
41399
E179
M
S
S
K
S
D
S
E
Q
P
S
P
A
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512522
574
64356
S380
E
E
N
L
S
S
K
S
E
S
E
Q
P
S
P
Chicken
Gallus gallus
XP_424818
543
60453
S349
N
M
S
S
K
S
E
S
D
Q
P
S
P
A
S
Frog
Xenopus laevis
NP_001087981
552
61635
S359
S
N
S
D
E
E
G
S
S
K
S
E
S
V
P
Zebra Danio
Brachydanio rerio
NP_001017819
555
62915
S361
D
D
N
T
F
T
R
S
D
S
D
Q
P
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651979
931
100212
S681
P
D
L
P
A
R
S
S
S
Q
Q
K
P
T
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782465
663
72269
A469
A
E
L
S
T
E
E
A
E
H
D
A
P
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.6
98.5
N.A.
98.4
63.7
N.A.
82.7
74.1
51
63.3
N.A.
27.3
N.A.
N.A.
39.5
Protein Similarity:
100
99.4
99.6
99.1
N.A.
99.1
64.4
N.A.
89.9
83.9
64
75.6
N.A.
41.5
N.A.
N.A.
54.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
86.6
26.6
13.3
53.3
N.A.
13.3
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
46.6
26.6
86.6
N.A.
46.6
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
0
0
9
0
0
0
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
17
0
9
0
9
0
0
59
0
17
0
0
0
0
% D
% Glu:
50
59
0
0
9
17
17
9
17
0
50
9
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
9
0
50
0
0
9
0
9
0
0
9
% K
% Leu:
0
0
17
9
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
9
9
0
17
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
59
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
9
0
0
0
0
0
9
9
9
84
0
75
% P
% Gln:
0
0
0
0
0
0
0
0
9
17
9
59
0
0
0
% Q
% Arg:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
25
17
59
59
17
84
17
59
17
9
9
75
17
% S
% Thr:
0
0
0
9
9
9
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _