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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLLT3 All Species: 25.45
Human Site: S460 Identified Species: 50.91
UniProt: P42568 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42568 NP_004520.2 568 63351 S460 S E S S S A S S P L H H E P P
Chimpanzee Pan troglodytes XP_001148491 567 63262 S459 S E S S S A S S P L H H E P P
Rhesus Macaque Macaca mulatta XP_001108646 570 63507 S462 S E S S S A S S P L H H E P P
Dog Lupus familis XP_538677 568 63352 S460 S E S S S A S S P L H H E P P
Cat Felis silvestris
Mouse Mus musculus A2AM29 569 63357 S461 S E S S S A S S P L H H E P P
Rat Rattus norvegicus NP_446170 370 41399 H265 S S A S S P L H H E P P P P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512522 574 64356 S466 I E S N S T S S P L H H D L P
Chicken Gallus gallus XP_424818 543 60453 S435 S D S N S A S S P P R H E P A
Frog Xenopus laevis NP_001087981 552 61635 A445 D S S D D S C A P S R G P A P
Zebra Danio Brachydanio rerio NP_001017819 555 62915 G447 S E S E N S S G S S P L P H N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651979 931 100212 I767 A G V T G A F I E P P V K A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782465 663 72269 K555 S P S P E I E K P K P V S K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 99.6 98.5 N.A. 98.4 63.7 N.A. 82.7 74.1 51 63.3 N.A. 27.3 N.A. N.A. 39.5
Protein Similarity: 100 99.4 99.6 99.1 N.A. 99.1 64.4 N.A. 89.9 83.9 64 75.6 N.A. 41.5 N.A. N.A. 54.6
P-Site Identity: 100 100 100 100 N.A. 100 26.6 N.A. 66.6 66.6 20 26.6 N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. 80 80 33.3 40 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 59 0 9 0 0 0 0 0 17 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 9 9 0 0 0 0 0 0 0 9 0 0 % D
% Glu: 0 59 0 9 9 0 9 0 9 9 0 0 50 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 9 0 0 9 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 9 9 0 50 59 0 9 0 % H
% Ile: 9 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 9 0 9 0 0 9 9 0 % K
% Leu: 0 0 0 0 0 0 9 0 0 50 0 9 0 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 17 9 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 9 0 9 0 9 0 0 75 17 34 9 25 59 59 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % R
% Ser: 75 17 84 50 67 17 67 59 9 17 0 0 9 0 17 % S
% Thr: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 9 0 0 0 0 0 0 0 0 17 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _