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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP2
All Species:
16.97
Human Site:
S139
Identified Species:
31.11
UniProt:
P42575
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42575
NP_116764.2
452
50685
S139
L
S
C
D
Y
D
L
S
L
P
F
P
V
C
E
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
Rhesus Macaque
Macaca mulatta
Q153Z0
421
47740
S117
S
E
E
E
N
E
E
S
K
D
E
E
R
A
A
Dog
Lupus familis
XP_848601
452
50347
S139
L
S
C
D
Y
D
L
S
L
T
F
P
M
C
E
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
S139
L
S
C
D
Y
D
T
S
L
P
F
S
V
C
E
Rat
Rattus norvegicus
P55215
452
50709
S139
L
S
C
D
Y
D
S
S
L
P
F
S
V
C
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506482
767
84465
S457
L
G
C
D
Y
D
S
S
L
P
F
P
T
H
E
Chicken
Gallus gallus
Q98943
424
47941
N114
L
E
Q
R
Y
G
S
N
L
P
L
P
L
S
E
Frog
Xenopus laevis
P55867
382
43370
Q97
E
H
A
P
S
P
I
Q
E
H
N
E
D
T
I
Zebra Danio
Brachydanio rerio
NP_001036160
435
49559
E115
S
L
S
L
P
T
Q
E
C
V
T
P
A
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01382
339
37345
S53
G
S
S
H
P
Y
G
S
G
A
I
G
Q
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
N165
L
H
S
S
D
R
H
N
Y
S
S
P
P
V
N
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
V125
P
T
Q
Q
V
P
L
V
W
P
A
R
D
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.7
22.5
89.8
N.A.
89.5
89.5
N.A.
47.9
67
22.1
49.7
N.A.
25
N.A.
25.2
27.6
Protein Similarity:
100
36.2
42
92.6
N.A.
93.3
93.8
N.A.
51.2
76.9
40.9
64.3
N.A.
40.7
N.A.
42.3
47.5
P-Site Identity:
100
0
6.6
86.6
N.A.
86.6
86.6
N.A.
73.3
40
0
6.6
N.A.
13.3
N.A.
13.3
13.3
P-Site Similarity:
100
0
20
93.3
N.A.
86.6
86.6
N.A.
73.3
53.3
6.6
6.6
N.A.
13.3
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
8
8
0
8
8
16
% A
% Cys:
0
0
39
0
0
0
0
0
8
0
0
0
0
31
0
% C
% Asp:
0
0
0
39
8
39
0
0
0
8
0
0
16
0
0
% D
% Glu:
8
16
8
8
0
8
8
8
8
0
8
16
0
0
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
39
0
0
0
0
% F
% Gly:
8
8
0
0
0
8
8
0
8
0
0
8
0
0
0
% G
% His:
0
16
0
8
0
0
8
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% K
% Leu:
54
8
0
8
0
0
24
0
47
0
8
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
16
0
0
8
0
0
0
8
% N
% Pro:
8
0
0
8
16
16
0
0
0
47
0
47
8
0
0
% P
% Gln:
0
0
16
8
0
0
8
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
8
0
0
0
0
0
8
8
0
8
% R
% Ser:
16
39
24
8
8
0
24
54
0
8
8
16
0
16
0
% S
% Thr:
0
8
0
0
0
8
8
0
0
8
8
0
8
8
8
% T
% Val:
0
0
0
0
8
0
0
8
0
8
0
0
24
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
47
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _