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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP2
All Species:
23.33
Human Site:
T109
Identified Species:
42.78
UniProt:
P42575
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42575
NP_116764.2
452
50685
T109
F
C
E
A
L
R
E
T
K
Q
G
H
L
E
D
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
Rhesus Macaque
Macaca mulatta
Q153Z0
421
47740
E87
H
P
K
Q
L
S
L
E
Y
Q
H
E
S
E
D
Dog
Lupus familis
XP_848601
452
50347
T109
F
C
V
A
L
R
E
T
K
Q
G
H
L
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
T109
F
C
E
A
L
R
E
T
R
Q
G
H
L
E
D
Rat
Rattus norvegicus
P55215
452
50709
T109
F
C
E
A
L
R
E
T
R
Q
G
H
L
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506482
767
84465
E427
A
F
C
A
A
L
R
E
T
K
Q
G
H
L
Q
Chicken
Gallus gallus
Q98943
424
47941
T84
F
C
E
A
L
Q
E
T
K
Q
Q
H
L
A
E
Frog
Xenopus laevis
P55867
382
43370
S67
V
K
K
K
G
E
Y
S
S
N
I
L
L
E
S
Zebra Danio
Brachydanio rerio
NP_001036160
435
49559
T85
F
C
S
A
L
K
E
T
E
Q
H
H
L
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01382
339
37345
P23
R
V
G
N
P
E
Q
P
N
D
H
T
D
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
S135
V
H
R
D
S
V
S
S
V
S
S
F
T
S
Y
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
S95
G
Y
S
A
S
G
P
S
Q
G
Q
M
G
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.7
22.5
89.8
N.A.
89.5
89.5
N.A.
47.9
67
22.1
49.7
N.A.
25
N.A.
25.2
27.6
Protein Similarity:
100
36.2
42
92.6
N.A.
93.3
93.8
N.A.
51.2
76.9
40.9
64.3
N.A.
40.7
N.A.
42.3
47.5
P-Site Identity:
100
0
26.6
93.3
N.A.
93.3
93.3
N.A.
6.6
73.3
13.3
60
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
0
33.3
93.3
N.A.
100
100
N.A.
13.3
86.6
26.6
73.3
N.A.
6.6
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
62
8
0
0
0
0
0
0
0
0
16
0
% A
% Cys:
0
47
8
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
39
% D
% Glu:
0
0
31
0
0
16
47
16
8
0
0
8
0
47
8
% E
% Phe:
47
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
8
0
8
8
0
0
0
8
31
8
8
0
0
% G
% His:
8
8
0
0
0
0
0
0
0
0
24
47
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
8
16
8
0
8
0
0
24
8
0
0
0
0
8
% K
% Leu:
0
0
0
0
54
8
8
0
0
0
0
8
54
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% N
% Pro:
0
8
0
0
8
0
8
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
8
8
0
8
54
24
0
0
8
8
% Q
% Arg:
8
0
8
0
0
31
8
0
16
0
0
0
0
0
0
% R
% Ser:
0
0
16
0
16
8
8
24
8
8
8
0
8
8
8
% S
% Thr:
0
0
0
0
0
0
0
47
8
0
0
8
8
0
8
% T
% Val:
16
8
8
0
0
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _