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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP2
All Species:
10.91
Human Site:
T158
Identified Species:
20
UniProt:
P42575
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42575
NP_116764.2
452
50685
T158
Y
K
K
L
R
L
S
T
D
T
V
E
H
S
L
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
K11
T
E
N
S
V
D
S
K
S
I
K
N
L
E
P
Rhesus Macaque
Macaca mulatta
Q153Z0
421
47740
P136
M
A
V
P
P
T
A
P
L
E
I
Q
G
A
Q
Dog
Lupus familis
XP_848601
452
50347
P158
Q
K
Q
L
R
L
S
P
D
T
V
E
H
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
T158
H
K
Q
L
R
L
S
T
D
A
T
E
H
S
L
Rat
Rattus norvegicus
P55215
452
50709
T158
H
K
Q
S
R
L
S
T
D
T
M
E
H
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506482
767
84465
E476
L
K
K
P
R
L
S
E
E
E
M
E
H
S
L
Chicken
Gallus gallus
Q98943
424
47941
E133
K
R
P
R
L
I
V
E
H
S
L
D
S
G
D
Frog
Xenopus laevis
P55867
382
43370
S116
I
N
S
V
I
P
C
S
A
E
E
F
K
N
I
Zebra Danio
Brachydanio rerio
NP_001036160
435
49559
D134
E
S
M
E
M
C
L
D
A
D
S
P
V
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01382
339
37345
K72
S
P
S
S
S
Y
R
K
N
V
A
K
M
V
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
S184
Q
P
S
S
A
N
S
S
F
T
G
C
S
S
L
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
G144
S
T
Q
M
D
A
S
G
S
Y
P
Q
T
M
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.7
22.5
89.8
N.A.
89.5
89.5
N.A.
47.9
67
22.1
49.7
N.A.
25
N.A.
25.2
27.6
Protein Similarity:
100
36.2
42
92.6
N.A.
93.3
93.8
N.A.
51.2
76.9
40.9
64.3
N.A.
40.7
N.A.
42.3
47.5
P-Site Identity:
100
6.6
0
80
N.A.
73.3
73.3
N.A.
60
0
0
0
N.A.
0
N.A.
26.6
6.6
P-Site Similarity:
100
13.3
26.6
86.6
N.A.
86.6
93.3
N.A.
73.3
33.3
26.6
6.6
N.A.
13.3
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
8
0
16
8
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
8
0
8
31
8
0
8
0
0
8
% D
% Glu:
8
8
0
8
0
0
0
16
8
24
8
39
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
8
0
8
8
0
% G
% His:
16
0
0
0
0
0
0
0
8
0
0
0
39
0
0
% H
% Ile:
8
0
0
0
8
8
0
0
0
8
8
0
0
0
8
% I
% Lys:
8
39
16
0
0
0
0
16
0
0
8
8
8
0
0
% K
% Leu:
8
0
0
24
8
39
8
0
8
0
8
0
8
0
47
% L
% Met:
8
0
8
8
8
0
0
0
0
0
16
0
8
8
0
% M
% Asn:
0
8
8
0
0
8
0
0
8
0
0
8
0
8
0
% N
% Pro:
0
16
8
16
8
8
0
16
0
0
8
8
0
0
8
% P
% Gln:
16
0
31
0
0
0
0
0
0
0
0
16
0
0
8
% Q
% Arg:
0
8
0
8
39
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
16
8
24
31
8
0
62
16
16
8
8
0
16
47
0
% S
% Thr:
8
8
0
0
0
8
0
24
0
31
8
0
8
8
16
% T
% Val:
0
0
8
8
8
0
8
0
0
8
16
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _