KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP2
All Species:
22.73
Human Site:
T325
Identified Species:
41.67
UniProt:
P42575
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42575
NP_116764.2
452
50685
T325
Q
A
C
R
G
D
E
T
D
R
G
V
D
Q
Q
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
Q161
K
P
K
L
F
I
I
Q
A
C
R
G
T
E
L
Rhesus Macaque
Macaca mulatta
Q153Z0
421
47740
A305
Q
A
C
R
G
S
G
A
G
I
V
W
F
T
T
Dog
Lupus familis
XP_848601
452
50347
T325
Q
A
C
R
G
D
E
T
D
R
G
V
D
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
T325
Q
A
C
R
G
D
E
T
D
R
G
V
D
Q
Q
Rat
Rattus norvegicus
P55215
452
50709
T325
Q
A
C
R
G
D
E
T
D
R
G
V
D
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506482
767
84465
T643
Q
A
C
R
G
D
E
T
D
R
G
V
D
Q
R
Chicken
Gallus gallus
Q98943
424
47941
T296
Q
A
C
R
G
D
E
T
D
R
G
V
D
Q
R
Frog
Xenopus laevis
P55867
382
43370
I266
W
D
K
P
K
V
I
I
I
Q
A
C
R
G
E
Zebra Danio
Brachydanio rerio
NP_001036160
435
49559
Q307
L
D
G
Q
E
R
T
Q
S
P
G
C
E
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01382
339
37345
M222
R
L
D
G
G
V
T
M
Q
R
S
Q
T
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
V376
V
L
D
S
V
D
G
V
P
A
F
L
R
R
G
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
P316
Q
A
N
A
Q
A
K
P
Q
V
D
A
Q
I
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.7
22.5
89.8
N.A.
89.5
89.5
N.A.
47.9
67
22.1
49.7
N.A.
25
N.A.
25.2
27.6
Protein Similarity:
100
36.2
42
92.6
N.A.
93.3
93.8
N.A.
51.2
76.9
40.9
64.3
N.A.
40.7
N.A.
42.3
47.5
P-Site Identity:
100
0
33.3
100
N.A.
100
100
N.A.
93.3
93.3
0
13.3
N.A.
13.3
N.A.
6.6
13.3
P-Site Similarity:
100
13.3
33.3
100
N.A.
100
100
N.A.
100
100
13.3
33.3
N.A.
26.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
62
0
8
0
8
0
8
8
8
8
8
0
0
0
% A
% Cys:
0
0
54
0
0
0
0
0
0
8
0
16
0
0
0
% C
% Asp:
0
16
16
0
0
54
0
0
47
0
8
0
47
0
0
% D
% Glu:
0
0
0
0
8
0
47
0
0
0
0
0
8
16
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
8
8
62
0
16
0
8
0
54
8
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
16
8
8
8
0
0
0
8
0
% I
% Lys:
8
0
16
0
8
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
16
0
8
0
0
0
0
0
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
8
0
8
0
0
0
8
8
8
0
0
0
0
0
% P
% Gln:
62
0
0
8
8
0
0
16
16
8
0
8
8
54
31
% Q
% Arg:
8
0
0
54
0
8
0
0
0
54
8
0
16
8
24
% R
% Ser:
0
0
0
8
0
8
0
0
8
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
16
47
0
0
0
0
16
8
16
% T
% Val:
8
0
0
0
8
16
0
8
0
8
8
47
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _