KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPP6
All Species:
21.82
Human Site:
T278
Identified Species:
40
UniProt:
P42658
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42658
NP_001034439.1
865
97588
T278
Q
A
I
R
V
V
S
T
G
K
E
G
V
I
Y
Chimpanzee
Pan troglodytes
Q5IS50
803
91393
K237
L
Y
E
E
E
I
L
K
T
H
I
A
H
W
W
Rhesus Macaque
Macaca mulatta
XP_001110451
727
82519
W164
L
K
T
H
I
A
H
W
W
S
P
D
G
T
R
Dog
Lupus familis
XP_532774
893
100079
T249
Q
A
I
R
V
V
S
T
G
K
E
G
V
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z218
804
91242
I236
D
W
L
Y
E
E
E
I
L
K
S
H
I
A
H
Rat
Rattus norvegicus
P46101
859
97283
T272
Q
A
I
R
V
V
S
T
G
K
E
G
V
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511273
877
98536
T290
Q
A
I
R
V
V
S
T
G
K
E
G
V
I
F
Chicken
Gallus gallus
XP_418545
849
96678
T264
Q
A
I
R
V
V
S
T
G
K
E
G
V
I
F
Frog
Xenopus laevis
NP_001085104
796
90480
E233
A
D
W
L
Y
E
E
E
I
L
H
S
H
V
A
Zebra Danio
Brachydanio rerio
NP_001108594
868
98173
T278
P
S
I
R
L
V
S
T
G
S
L
G
V
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q7JKY3
799
91347
E236
G
L
F
D
W
I
Y
E
E
E
I
F
G
R
K
Sea Urchin
Strong. purpuratus
XP_794889
740
84108
F177
P
N
S
A
G
L
V
F
V
Y
K
N
N
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P18962
818
93386
F245
W
V
Y
E
E
E
V
F
E
D
D
K
A
A
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.2
77.5
62.3
N.A.
85.1
92.7
N.A.
83.5
80.9
47.8
60.1
N.A.
N.A.
N.A.
24.1
29.8
Protein Similarity:
100
91.9
80.1
69.1
N.A.
89.1
96.3
N.A.
90.4
89.5
65
75.9
N.A.
N.A.
N.A.
43.8
49.9
P-Site Identity:
100
0
0
100
N.A.
6.6
100
N.A.
93.3
93.3
0
60
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
13.3
6.6
100
N.A.
26.6
100
N.A.
100
100
6.6
80
N.A.
N.A.
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
39
0
8
0
8
0
0
0
0
0
8
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
8
0
0
0
0
0
8
8
8
0
0
0
% D
% Glu:
0
0
8
16
24
24
16
16
16
8
39
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
16
0
0
0
8
0
0
24
% F
% Gly:
8
0
0
0
8
0
0
0
47
0
0
47
16
0
0
% G
% His:
0
0
0
8
0
0
8
0
0
8
8
8
16
0
8
% H
% Ile:
0
0
47
0
8
16
0
8
8
0
16
0
8
47
0
% I
% Lys:
0
8
0
0
0
0
0
8
0
47
8
8
0
0
8
% K
% Leu:
16
8
8
8
8
8
8
0
8
8
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
39
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
47
0
0
0
0
0
0
0
0
0
8
8
% R
% Ser:
0
8
8
0
0
0
47
0
0
16
8
8
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
47
8
0
0
0
0
8
0
% T
% Val:
0
8
0
0
39
47
16
0
8
0
0
0
47
8
0
% V
% Trp:
8
8
8
0
8
0
0
8
8
0
0
0
0
8
16
% W
% Tyr:
0
8
8
8
8
0
8
0
0
8
0
0
0
0
31
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _