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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TEC
All Species:
22.73
Human Site:
S550
Identified Species:
50
UniProt:
P42680
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42680
NP_003206.2
631
73581
S550
S
S
K
S
D
V
W
S
F
G
V
L
M
W
E
Chimpanzee
Pan troglodytes
XP_517310
631
73535
S550
S
S
K
S
D
V
W
S
F
G
V
L
M
W
E
Rhesus Macaque
Macaca mulatta
XP_001103213
630
73464
S549
S
S
K
S
D
V
W
S
F
G
V
L
M
W
E
Dog
Lupus familis
XP_539259
631
73589
S550
S
S
K
S
D
V
W
S
F
G
V
L
M
W
E
Cat
Felis silvestris
Mouse
Mus musculus
P24604
630
73408
S549
S
S
K
S
D
V
W
S
F
G
V
L
M
W
E
Rat
Rattus norvegicus
P50545
524
59135
L445
V
W
S
F
G
I
L
L
M
E
I
V
T
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515402
583
67167
S504
S
S
K
S
D
V
W
S
F
G
V
L
M
W
E
Chicken
Gallus gallus
Q8JH64
657
75860
D577
S
K
F
S
S
K
S
D
V
W
S
F
G
V
L
Frog
Xenopus laevis
P13116
532
59718
E453
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
Zebra Danio
Brachydanio rerio
NP_001108215
622
71783
P542
K
F
P
V
K
W
S
P
P
E
V
F
N
F
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08630
786
87374
W707
F
S
S
K
S
D
V
W
A
Y
G
V
L
M
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
96.1
N.A.
94.1
32.3
N.A.
78.7
54.7
33.5
65.6
N.A.
39.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.6
97.9
N.A.
97.1
50
N.A.
85.9
71
49.2
79.4
N.A.
54.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
13.3
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
13.3
13.3
13.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
55
10
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
19
0
0
0
0
55
% E
% Phe:
10
19
10
10
0
0
0
0
55
0
0
19
0
10
0
% F
% Gly:
0
0
10
0
10
0
0
0
0
55
10
0
19
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
10
10
55
10
10
10
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
10
10
10
10
10
0
0
55
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
55
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
73
64
19
64
19
0
19
55
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
10
10
0
10
0
0
% T
% Val:
10
0
0
10
0
55
10
0
10
0
64
19
0
10
10
% V
% Trp:
0
10
0
0
0
10
55
10
0
10
0
0
0
55
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _