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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRPPRC All Species: 8.48
Human Site: S23 Identified Species: 20.74
UniProt: P42704 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42704 NP_573566.2 1394 157905 S23 A A P R L P L S L R L L P G G
Chimpanzee Pan troglodytes XP_001143797 1394 157780 S23 A A P R L P L S L R L L P G G
Rhesus Macaque Macaca mulatta XP_001107298 1029 116102
Dog Lupus familis XP_531800 1393 157638 S23 A A P R L P L S L R L L A S G
Cat Felis silvestris
Mouse Mus musculus Q6PB66 1392 156596 L22 A A A P R L P L S L R L P A G
Rat Rattus norvegicus Q5SGE0 1392 156634 L22 A A V P R L P L S L R L P A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234903 1371 155609 P25 L R P L L L P P A P A A A R N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001136064 1436 160823 L42 Y S G A I G T L R V G V C G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523596 1412 157245 D71 Q I R R L D Q D V R R I G R I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190098 1315 149084 Q23 D S T T E V A Q Q P I R S D N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 60.3 79.6 N.A. 75.2 76.3 N.A. N.A. 57.3 N.A. 49.2 N.A. 29.2 N.A. N.A. 33
Protein Similarity: 100 99.7 65.2 88.7 N.A. 86.2 86.5 N.A. N.A. 73 N.A. 68.6 N.A. 50.3 N.A. N.A. 53.4
P-Site Identity: 100 100 0 86.6 N.A. 33.3 33.3 N.A. N.A. 13.3 N.A. 6.6 N.A. 20 N.A. N.A. 0
P-Site Similarity: 100 100 0 86.6 N.A. 33.3 33.3 N.A. N.A. 13.3 N.A. 26.6 N.A. 33.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 50 10 10 0 0 10 0 10 0 10 10 20 20 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 10 0 0 0 0 10 0 10 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 10 0 0 0 0 10 0 10 30 50 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 10 0 0 0 0 0 10 10 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 10 50 30 30 30 30 20 30 50 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % N
% Pro: 0 0 40 20 0 30 30 10 0 20 0 0 40 0 0 % P
% Gln: 10 0 0 0 0 0 10 10 10 0 0 0 0 0 0 % Q
% Arg: 0 10 10 40 20 0 0 0 10 40 30 10 0 20 10 % R
% Ser: 0 20 0 0 0 0 0 30 20 0 0 0 10 10 0 % S
% Thr: 0 0 10 10 0 0 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 10 0 0 10 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _