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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRPPRC All Species: 24.85
Human Site: Y565 Identified Species: 60.74
UniProt: P42704 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42704 NP_573566.2 1394 157905 Y565 S E I T E L L Y K D G R Y C Q
Chimpanzee Pan troglodytes XP_001143797 1394 157780 Y565 S E I T E L L Y K D G R Y C Q
Rhesus Macaque Macaca mulatta XP_001107298 1029 116102 R321 K E M T M Q L R S S E L E S R
Dog Lupus familis XP_531800 1393 157638 Y565 S K I T E L L Y K D G R Y C Q
Cat Felis silvestris
Mouse Mus musculus Q6PB66 1392 156596 Y564 S K I T E L L Y K D E R Y C S
Rat Rattus norvegicus Q5SGE0 1392 156634 Y564 S K I T E L L Y K D D R Y C Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234903 1371 155609 Y548 S Q I T E L L Y K D E R Y C L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001136064 1436 160823 Y588 A K I T E L L Y K D A R F A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523596 1412 157245 K602 K I L K G L V K Q G L S I S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190098 1315 149084 V535 L S R E G L Y V T G S R Y R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 60.3 79.6 N.A. 75.2 76.3 N.A. N.A. 57.3 N.A. 49.2 N.A. 29.2 N.A. N.A. 33
Protein Similarity: 100 99.7 65.2 88.7 N.A. 86.2 86.5 N.A. N.A. 73 N.A. 68.6 N.A. 50.3 N.A. N.A. 53.4
P-Site Identity: 100 100 20 93.3 N.A. 80 86.6 N.A. N.A. 80 N.A. 60 N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 100 33.3 100 N.A. 86.6 93.3 N.A. N.A. 86.6 N.A. 80 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 10 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 60 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 70 10 0 0 0 0 % D
% Glu: 0 30 0 10 70 0 0 0 0 0 30 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 20 0 0 0 0 20 30 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 70 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 20 40 0 10 0 0 0 10 70 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 0 90 80 0 0 0 10 10 0 0 10 % L
% Met: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 10 0 0 10 0 0 0 0 0 40 % Q
% Arg: 0 0 10 0 0 0 0 10 0 0 0 80 0 10 10 % R
% Ser: 60 10 0 0 0 0 0 0 10 10 10 10 0 20 20 % S
% Thr: 0 0 0 80 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 70 0 0 0 0 70 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _