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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACAA2 All Species: 7.88
Human Site: S151 Identified Species: 14.44
UniProt: P42765 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42765 NP_006102.2 397 41924 S151 L E D S L W V S L T D Q H V Q
Chimpanzee Pan troglodytes XP_512127 656 69275 S410 L E D S L W A S L T D Q H V Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547690 382 40277 N139 L S P T E L Q N L D Y N S M S
Cat Felis silvestris
Mouse Mus musculus Q8BWT1 397 41839 G151 L E D T L W A G L T D Q H V K
Rat Rattus norvegicus P13437 397 41852 G151 L E D T L W A G L T D Q H V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508051 393 41091 G147 L V D T L W E G L T D Q H V K
Chicken Gallus gallus NP_001006571 397 41666 G151 L E D T L W E G L T D T Y V K
Frog Xenopus laevis NP_001080732 397 41888 G151 M E D T L W A G L T D S L I K
Zebra Danio Brachydanio rerio NP_998217 397 41768 G151 L E D T L W A G L T D L N I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523528 398 41592 G153 L E D A L W A G L T D T Y C K
Honey Bee Apis mellifera XP_391843 399 42485 G153 F E D S L W L G F S D T Y C N
Nematode Worm Caenorhab. elegans NP_499752 394 41272 S150 F E D M L W D S L S D P Y A K
Sea Urchin Strong. purpuratus XP_793074 369 38553 T128 N M S M A P Y T L R G A R F G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60 N.A. 67 N.A. 87.6 87.4 N.A. 83.6 79.3 73.8 76.8 N.A. 60.2 58.1 55.4 60.4
Protein Similarity: 100 60.2 N.A. 79.3 N.A. 96.2 95.9 N.A. 91.6 90.4 87.1 88.6 N.A. 74.8 75.1 72.8 73.8
P-Site Identity: 100 93.3 N.A. 13.3 N.A. 73.3 73.3 N.A. 66.6 60 46.6 53.3 N.A. 53.3 40 46.6 6.6
P-Site Similarity: 100 93.3 N.A. 33.3 N.A. 86.6 86.6 N.A. 80 80 73.3 80 N.A. 73.3 60 66.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 47 0 0 0 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % C
% Asp: 0 0 85 0 0 0 8 0 0 8 85 0 0 0 0 % D
% Glu: 0 77 0 0 8 0 16 0 0 0 0 0 0 0 0 % E
% Phe: 16 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 62 0 0 8 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 62 % K
% Leu: 70 0 0 0 85 8 8 0 93 0 0 8 8 0 0 % L
% Met: 8 8 0 16 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 8 0 0 0 0 0 0 8 0 0 0 8 8 0 8 % N
% Pro: 0 0 8 0 0 8 0 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 39 0 0 16 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % R
% Ser: 0 8 8 24 0 0 0 24 0 16 0 8 8 0 8 % S
% Thr: 0 0 0 54 0 0 0 8 0 70 0 24 0 0 0 % T
% Val: 0 8 0 0 0 0 8 0 0 0 0 0 0 47 0 % V
% Trp: 0 0 0 0 0 85 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 8 0 31 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _