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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAA2
All Species:
20.3
Human Site:
S333
Identified Species:
37.22
UniProt:
P42765
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42765
NP_006102.2
397
41924
S333
Q
Y
L
A
V
E
R
S
L
D
L
D
I
S
K
Chimpanzee
Pan troglodytes
XP_512127
656
69275
S592
Q
Y
L
A
V
E
R
S
L
D
L
D
I
S
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547690
382
40277
S318
Q
Y
L
A
V
E
K
S
L
D
L
D
P
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWT1
397
41839
A333
Q
F
L
S
V
Q
K
A
L
D
L
D
P
S
K
Rat
Rattus norvegicus
P13437
397
41852
S333
Q
F
L
A
V
Q
K
S
L
D
L
D
P
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508051
393
41091
S329
Q
Y
L
A
V
E
K
S
L
G
L
D
P
S
K
Chicken
Gallus gallus
NP_001006571
397
41666
V333
Q
Y
L
A
V
E
K
V
L
G
L
D
P
E
K
Frog
Xenopus laevis
NP_001080732
397
41888
A333
Q
Y
L
A
V
E
K
A
L
G
L
N
R
E
K
Zebra Danio
Brachydanio rerio
NP_998217
397
41768
S333
Q
Y
L
S
V
A
K
S
L
G
L
D
P
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523528
398
41592
A335
Q
T
L
A
C
A
D
A
L
K
L
D
T
S
K
Honey Bee
Apis mellifera
XP_391843
399
42485
E335
Q
T
L
A
C
V
K
E
L
K
L
D
I
N
K
Nematode Worm
Caenorhab. elegans
NP_499752
394
41272
E331
Q
A
L
A
V
Q
R
E
L
G
I
P
M
E
K
Sea Urchin
Strong. purpuratus
XP_793074
369
38553
G307
R
N
A
L
E
R
A
G
L
K
L
S
D
M
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60
N.A.
67
N.A.
87.6
87.4
N.A.
83.6
79.3
73.8
76.8
N.A.
60.2
58.1
55.4
60.4
Protein Similarity:
100
60.2
N.A.
79.3
N.A.
96.2
95.9
N.A.
91.6
90.4
87.1
88.6
N.A.
74.8
75.1
72.8
73.8
P-Site Identity:
100
100
N.A.
86.6
N.A.
60
73.3
N.A.
80
66.6
60
60
N.A.
53.3
53.3
46.6
13.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
86.6
73.3
80
73.3
N.A.
60
66.6
66.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
77
0
16
8
24
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
39
0
77
8
0
8
% D
% Glu:
0
0
0
0
8
47
0
16
0
0
0
0
0
31
0
% E
% Phe:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
39
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
24
0
0
% I
% Lys:
0
0
0
0
0
0
62
0
0
24
0
0
0
0
93
% K
% Leu:
0
0
93
8
0
0
0
0
100
0
93
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
47
0
0
% P
% Gln:
93
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
8
24
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
16
0
0
0
47
0
0
0
8
0
54
0
% S
% Thr:
0
16
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
77
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _