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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAA2
All Species:
22.12
Human Site:
Y198
Identified Species:
40.56
UniProt:
P42765
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42765
NP_006102.2
397
41924
Y198
K
A
A
N
D
A
G
Y
F
N
D
E
M
A
P
Chimpanzee
Pan troglodytes
XP_512127
656
69275
Y457
K
A
A
N
D
A
G
Y
F
N
D
E
M
A
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547690
382
40277
Q186
N
Q
A
E
I
K
N
Q
L
N
E
M
Q
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWT1
397
41839
Y198
K
A
A
N
E
A
G
Y
F
N
E
E
M
A
P
Rat
Rattus norvegicus
P13437
397
41852
Y198
K
A
A
N
E
A
G
Y
F
N
E
E
M
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508051
393
41091
C194
K
A
A
N
D
G
G
C
F
T
N
E
M
V
P
Chicken
Gallus gallus
NP_001006571
397
41666
H198
K
A
A
Q
D
A
G
H
F
N
A
E
M
A
P
Frog
Xenopus laevis
NP_001080732
397
41888
Y198
K
A
A
Q
D
S
G
Y
F
A
A
E
M
A
P
Zebra Danio
Brachydanio rerio
NP_998217
397
41768
Y198
K
A
A
H
E
A
G
Y
F
N
A
E
I
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523528
398
41592
A200
E
K
G
Q
K
E
G
A
F
N
A
E
I
T
P
Honey Bee
Apis mellifera
XP_391843
399
42485
R200
K
A
A
N
D
A
G
R
F
N
E
E
I
A
P
Nematode Worm
Caenorhab. elegans
NP_499752
394
41272
V197
K
K
A
Q
E
A
G
V
Y
K
N
E
I
V
G
Sea Urchin
Strong. purpuratus
XP_793074
369
38553
T175
L
G
A
K
Y
D
V
T
R
E
D
C
D
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60
N.A.
67
N.A.
87.6
87.4
N.A.
83.6
79.3
73.8
76.8
N.A.
60.2
58.1
55.4
60.4
Protein Similarity:
100
60.2
N.A.
79.3
N.A.
96.2
95.9
N.A.
91.6
90.4
87.1
88.6
N.A.
74.8
75.1
72.8
73.8
P-Site Identity:
100
100
N.A.
13.3
N.A.
86.6
86.6
N.A.
66.6
80
73.3
73.3
N.A.
33.3
80
33.3
13.3
P-Site Similarity:
100
100
N.A.
26.6
N.A.
100
100
N.A.
73.3
86.6
80
93.3
N.A.
46.6
93.3
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
93
0
0
62
0
8
0
8
31
0
0
62
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
47
8
0
0
0
0
24
0
8
0
0
% D
% Glu:
8
0
0
8
31
8
0
0
0
8
31
85
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
77
0
0
0
0
0
8
% F
% Gly:
0
8
8
0
0
8
85
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
31
0
0
% I
% Lys:
77
16
0
8
8
8
0
0
0
8
0
0
0
0
8
% K
% Leu:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
54
0
0
% M
% Asn:
8
0
0
47
0
0
8
0
0
70
16
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
77
% P
% Gln:
0
8
0
31
0
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
8
8
0
0
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
47
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _