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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAA2
All Species:
44.85
Human Site:
Y376
Identified Species:
82.22
UniProt:
P42765
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42765
NP_006102.2
397
41924
Y376
L
R
R
R
G
G
K
Y
A
V
G
S
A
C
I
Chimpanzee
Pan troglodytes
XP_512127
656
69275
Y635
L
R
R
R
G
G
K
Y
A
V
G
S
A
C
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547690
382
40277
Y361
L
R
R
R
G
G
K
Y
A
M
G
S
A
C
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWT1
397
41839
Y376
L
R
R
R
G
G
K
Y
A
V
G
S
A
C
I
Rat
Rattus norvegicus
P13437
397
41852
Y376
L
R
R
R
G
G
K
Y
A
V
G
S
A
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508051
393
41091
Y372
L
R
R
R
G
G
K
Y
A
I
G
S
A
C
I
Chicken
Gallus gallus
NP_001006571
397
41666
Y376
L
R
R
R
G
G
K
Y
A
V
G
S
A
C
I
Frog
Xenopus laevis
NP_001080732
397
41888
Y376
L
K
R
R
G
G
K
Y
A
V
G
S
A
C
I
Zebra Danio
Brachydanio rerio
NP_998217
397
41768
Y376
L
R
R
R
G
G
K
Y
A
V
G
S
A
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523528
398
41592
Y378
L
Q
R
K
K
L
K
Y
G
I
G
S
A
C
I
Honey Bee
Apis mellifera
XP_391843
399
42485
S378
L
R
R
R
K
T
G
S
L
G
I
G
S
A
C
Nematode Worm
Caenorhab. elegans
NP_499752
394
41272
Y374
L
H
R
R
N
V
K
Y
G
I
G
S
A
C
I
Sea Urchin
Strong. purpuratus
XP_793074
369
38553
M349
V
N
G
G
A
I
A
M
G
H
P
V
G
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60
N.A.
67
N.A.
87.6
87.4
N.A.
83.6
79.3
73.8
76.8
N.A.
60.2
58.1
55.4
60.4
Protein Similarity:
100
60.2
N.A.
79.3
N.A.
96.2
95.9
N.A.
91.6
90.4
87.1
88.6
N.A.
74.8
75.1
72.8
73.8
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
93.3
100
93.3
100
N.A.
60
26.6
66.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
80
33.3
73.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
70
0
0
0
85
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
85
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
70
70
8
0
24
8
85
8
8
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
24
8
0
0
0
85
% I
% Lys:
0
8
0
8
16
0
85
0
0
0
0
0
0
0
0
% K
% Leu:
93
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
70
93
85
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
0
0
85
8
0
8
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
8
0
0
0
54
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _