KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKN2A
All Species:
3.79
Human Site:
S152
Identified Species:
9.26
UniProt:
P42771
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42771
NP_000068.1
156
16533
S152
I
D
A
A
E
G
P
S
D
I
P
D
_
_
_
Chimpanzee
Pan troglodytes
XP_520513
357
38160
L353
I
D
A
A
E
G
P
L
D
I
P
D
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001098554
308
33161
S304
I
Y
A
A
E
G
P
S
C
I
P
D
_
_
_
Dog
Lupus familis
XP_853946
166
17636
D156
I
G
A
Q
D
L
M
D
I
L
Q
G
H
T
V
Cat
Felis silvestris
Mouse
Mus musculus
P55271
130
13770
A126
D
I
A
R
Y
L
H
A
A
T
G
D
_
_
_
Rat
Rattus norvegicus
P55272
130
13730
A126
D
I
A
R
Y
L
H
A
A
T
G
D
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514482
119
12661
Chicken
Gallus gallus
NP_989764
139
14486
Frog
Xenopus laevis
NP_001090330
125
13495
L121
D
L
K
A
K
L
L
L
L
G
Y
R
_
_
_
Zebra Danio
Brachydanio rerio
XP_001923222
170
18559
A146
G
Y
T
P
R
D
L
A
F
M
H
Q
K
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.4
48
38.5
N.A.
73
71.1
N.A.
48.7
52.5
41.6
38.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
43.4
48.7
50
N.A.
76.2
75.6
N.A.
53.2
60.9
54.4
52.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
91.6
83.3
13.3
N.A.
16.6
16.6
N.A.
0
0
8.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
91.6
83.3
26.6
N.A.
25
25
N.A.
0
0
16.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
60
40
0
0
0
30
20
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
30
20
0
0
10
10
0
10
20
0
0
50
0
0
0
% D
% Glu:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
30
0
0
0
10
20
10
0
0
0
% G
% His:
0
0
0
0
0
0
20
0
0
0
10
0
10
10
0
% H
% Ile:
40
20
0
0
0
0
0
0
10
30
0
0
0
0
0
% I
% Lys:
0
0
10
0
10
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
10
0
0
0
40
20
20
10
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
30
0
0
0
30
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
10
10
0
0
0
% Q
% Arg:
0
0
0
20
10
0
0
0
0
0
0
10
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
20
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
20
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
60
60
60
% _