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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKN2A
All Species:
22.73
Human Site:
T77
Identified Species:
55.56
UniProt:
P42771
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42771
NP_000068.1
156
16533
T77
P
N
C
A
D
P
A
T
L
T
R
P
V
H
D
Chimpanzee
Pan troglodytes
XP_520513
357
38160
T278
P
N
C
A
D
P
A
T
L
T
R
P
V
H
D
Rhesus Macaque
Macaca mulatta
XP_001098554
308
33161
T229
P
N
C
A
D
P
A
T
L
T
R
P
V
H
D
Dog
Lupus familis
XP_853946
166
17636
T73
S
P
N
V
Q
D
A
T
G
T
T
P
A
H
D
Cat
Felis silvestris
Mouse
Mus musculus
P55271
130
13770
T71
P
N
C
A
D
P
A
T
L
T
R
P
V
H
D
Rat
Rattus norvegicus
P55272
130
13730
T71
P
N
C
A
D
P
A
T
L
T
R
P
V
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514482
119
12661
R62
D
V
P
D
A
W
G
R
L
P
V
D
L
A
L
Chicken
Gallus gallus
NP_989764
139
14486
T74
P
N
R
P
D
P
R
T
G
C
R
P
A
H
D
Frog
Xenopus laevis
NP_001090330
125
13495
V64
D
Y
G
A
D
P
S
V
P
D
P
S
T
G
T
Zebra Danio
Brachydanio rerio
XP_001923222
170
18559
L71
P
N
V
R
D
P
I
L
G
L
T
V
I
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.4
48
38.5
N.A.
73
71.1
N.A.
48.7
52.5
41.6
38.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
43.4
48.7
50
N.A.
76.2
75.6
N.A.
53.2
60.9
54.4
52.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
40
N.A.
100
100
N.A.
6.6
60
20
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
13.3
60
26.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
60
10
0
60
0
0
0
0
0
20
10
0
% A
% Cys:
0
0
50
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
20
0
0
10
80
10
0
0
0
10
0
10
0
0
80
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
10
0
30
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
60
10
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
70
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
70
10
10
10
0
80
0
0
10
10
10
70
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
0
10
10
0
0
60
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
70
0
60
20
0
10
0
10
% T
% Val:
0
10
10
10
0
0
0
10
0
0
10
10
50
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _