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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKN2B
All Species:
7.27
Human Site:
S14
Identified Species:
20
UniProt:
P42772
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42772
NP_004927.2
138
14722
S14
G
M
P
S
G
G
G
S
D
E
G
L
A
S
A
Chimpanzee
Pan troglodytes
NP_001139762
156
16540
S12
A
G
S
S
M
E
P
S
A
D
W
L
A
T
A
Rhesus Macaque
Macaca mulatta
XP_001107263
138
14703
S14
G
M
P
S
G
G
G
S
D
E
G
L
T
S
A
Dog
Lupus familis
XP_853946
166
17636
A15
A
G
D
R
L
S
G
A
A
A
R
G
D
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
P55271
130
13770
Q18
A
T
A
A
A
R
G
Q
V
E
T
V
R
Q
L
Rat
Rattus norvegicus
P55272
130
13730
Q18
A
T
A
A
A
R
G
Q
V
E
T
V
R
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989764
139
14486
A32
V
K
E
L
L
D
G
A
A
D
P
N
A
V
N
Frog
Xenopus laevis
NP_001090330
125
13495
S12
A
N
T
L
C
C
A
S
A
R
G
D
V
N
L
Zebra Danio
Brachydanio rerio
XP_001923222
170
18559
L19
T
A
A
A
I
G
D
L
M
E
V
E
Q
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.4
98.5
39.7
N.A.
82.6
82.6
N.A.
N.A.
56.8
45.6
21.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75
98.5
51.2
N.A.
86.9
87.6
N.A.
N.A.
66.9
60.1
35.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
93.3
6.6
N.A.
13.3
13.3
N.A.
N.A.
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
93.3
13.3
N.A.
26.6
26.6
N.A.
N.A.
26.6
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
56
12
34
34
23
0
12
23
45
12
0
0
34
0
34
% A
% Cys:
0
0
0
0
12
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
12
12
0
23
23
0
12
12
0
0
% D
% Glu:
0
0
12
0
0
12
0
0
0
56
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
23
23
0
0
23
34
67
0
0
0
34
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
23
23
0
0
12
0
0
0
34
0
0
45
% L
% Met:
0
23
0
0
12
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
12
0
12
12
% N
% Pro:
0
0
23
0
0
0
12
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
23
0
0
0
0
12
23
12
% Q
% Arg:
0
0
0
12
0
23
0
0
0
12
12
0
23
0
0
% R
% Ser:
0
0
12
34
0
12
0
45
0
0
0
0
0
23
0
% S
% Thr:
12
23
12
0
0
0
0
0
0
0
23
0
12
23
0
% T
% Val:
12
0
0
0
0
0
0
0
23
0
12
23
12
23
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _