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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKN2B
All Species:
16.36
Human Site:
Y131
Identified Species:
45
UniProt:
P42772
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42772
NP_004927.2
138
14722
Y131
G
H
R
D
V
A
G
Y
L
R
T
A
T
G
D
Chimpanzee
Pan troglodytes
NP_001139762
156
16540
Y129
G
H
R
D
V
A
R
Y
L
R
A
A
A
G
G
Rhesus Macaque
Macaca mulatta
XP_001107263
138
14703
Y131
G
H
R
D
V
A
G
Y
L
R
A
A
T
G
D
Dog
Lupus familis
XP_853946
166
17636
I157
G
A
Q
D
L
M
D
I
L
Q
G
H
T
V
V
Cat
Felis silvestris
Mouse
Mus musculus
P55271
130
13770
Y123
G
H
R
D
I
A
R
Y
L
H
A
A
T
G
D
Rat
Rattus norvegicus
P55272
130
13730
Y123
G
H
R
D
I
A
R
Y
L
H
A
A
T
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989764
139
14486
Y126
P
H
G
P
V
G
C
Y
L
R
R
L
P
A
L
Frog
Xenopus laevis
NP_001090330
125
13495
P113
R
P
I
D
L
A
S
P
D
L
K
A
K
L
L
Zebra Danio
Brachydanio rerio
XP_001923222
170
18559
F123
G
H
L
D
V
V
Q
F
L
V
T
H
C
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.4
98.5
39.7
N.A.
82.6
82.6
N.A.
N.A.
56.8
45.6
21.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75
98.5
51.2
N.A.
86.9
87.6
N.A.
N.A.
66.9
60.1
35.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
73.3
93.3
26.6
N.A.
73.3
73.3
N.A.
N.A.
33.3
20
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
93.3
46.6
N.A.
80
80
N.A.
N.A.
33.3
26.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
67
0
0
0
0
45
67
12
12
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% C
% Asp:
0
0
0
89
0
0
12
0
12
0
0
0
0
0
45
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
78
0
12
0
0
12
23
0
0
0
12
0
0
56
12
% G
% His:
0
78
0
0
0
0
0
0
0
23
0
23
0
0
0
% H
% Ile:
0
0
12
0
23
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% K
% Leu:
0
0
12
0
23
0
0
0
89
12
0
12
0
12
23
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
0
12
0
0
0
12
0
0
0
0
12
0
0
% P
% Gln:
0
0
12
0
0
0
12
0
0
12
0
0
0
0
0
% Q
% Arg:
12
0
56
0
0
0
34
0
0
45
12
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
23
0
56
0
12
% T
% Val:
0
0
0
0
56
12
0
0
0
12
0
0
0
23
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _