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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECE1
All Species:
20
Human Site:
S19
Identified Species:
44
UniProt:
P42892
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42892
NP_001106818.1
770
87164
S19
L
L
S
A
L
G
M
S
T
Y
K
R
A
T
L
Chimpanzee
Pan troglodytes
XP_001162780
770
87130
S19
L
L
S
A
L
G
M
S
T
Y
K
R
A
T
L
Rhesus Macaque
Macaca mulatta
XP_001099089
767
86923
S16
L
H
L
A
L
Q
M
S
T
Y
K
R
A
T
L
Dog
Lupus familis
XP_544514
768
87034
S16
L
H
L
A
L
Q
M
S
T
Y
K
R
A
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q4PZA2
769
87054
S18
A
L
A
A
L
G
M
S
T
Y
K
R
A
T
L
Rat
Rattus norvegicus
P42893
762
86107
K21
W
S
S
F
F
L
G
K
K
G
P
G
L
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511376
694
79095
Chicken
Gallus gallus
NP_990048
752
84967
D16
L
D
D
E
D
P
L
D
S
I
S
E
S
D
G
Frog
Xenopus laevis
NP_001080378
766
87192
S16
G
H
F
S
F
Q
M
S
A
Y
K
R
A
T
L
Zebra Danio
Brachydanio rerio
NP_001071260
752
85167
D16
L
E
E
E
E
L
L
D
T
G
S
D
G
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16796
848
97043
S26
Q
M
Q
L
I
T
I
S
E
N
S
D
I
P
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
94.1
N.A.
95
91
N.A.
74.2
81
75.8
65.8
N.A.
N.A.
N.A.
36.5
N.A.
Protein Similarity:
100
99.6
97.9
96.7
N.A.
97.9
94.1
N.A.
81.4
89
86.8
82.3
N.A.
N.A.
N.A.
55.5
N.A.
P-Site Identity:
100
100
80
80
N.A.
86.6
13.3
N.A.
0
6.6
53.3
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
80
80
N.A.
93.3
20
N.A.
0
26.6
60
20
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
46
0
0
0
0
10
0
0
0
55
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
10
0
0
19
0
0
0
19
0
10
0
% D
% Glu:
0
10
10
19
10
0
0
0
10
0
0
10
0
0
0
% E
% Phe:
0
0
10
10
19
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
28
10
0
0
19
0
10
10
0
10
% G
% His:
0
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
10
0
0
10
10
0
% I
% Lys:
0
0
0
0
0
0
0
10
10
0
55
0
0
0
0
% K
% Leu:
55
28
19
10
46
19
19
0
0
0
0
0
10
0
55
% L
% Met:
0
10
0
0
0
0
55
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
10
0
0
10
0
% P
% Gln:
10
0
10
0
0
28
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% R
% Ser:
0
10
28
10
0
0
0
64
10
0
28
0
10
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
55
0
0
0
0
64
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _