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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC1A3
All Species:
30
Human Site:
Y71
Identified Species:
82.5
UniProt:
P43003
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43003
NP_004163.3
542
59572
Y71
L
G
F
T
L
R
P
Y
R
M
S
Y
R
E
V
Chimpanzee
Pan troglodytes
XP_001146398
542
59526
Y71
L
G
F
T
L
R
P
Y
R
M
S
Y
R
E
V
Rhesus Macaque
Macaca mulatta
XP_001094417
542
59560
Y71
L
G
F
T
L
R
P
Y
R
M
S
Y
R
E
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P56564
543
59604
Y71
L
G
F
A
L
R
P
Y
K
M
S
Y
R
E
V
Rat
Rattus norvegicus
P24942
543
59679
Y71
L
G
F
A
L
R
P
Y
K
M
S
Y
R
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425011
543
59310
Y71
L
G
F
S
L
R
S
Y
K
M
S
Y
R
E
V
Frog
Xenopus laevis
NP_001083306
542
59629
Y71
L
G
F
S
V
R
K
Y
H
M
T
F
R
E
I
Zebra Danio
Brachydanio rerio
NP_997805
537
58803
Y71
L
G
F
G
L
R
P
Y
K
M
S
Y
R
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10901
503
54657
K64
E
L
L
M
H
M
L
K
M
M
I
L
P
L
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
N.A.
N.A.
96.5
96.6
N.A.
N.A.
88.9
85.7
76
N.A.
N.A.
N.A.
46.6
N.A.
Protein Similarity:
100
100
99.8
N.A.
N.A.
99
99
N.A.
N.A.
96.3
94.8
87.6
N.A.
N.A.
N.A.
66
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
N.A.
80
53.3
86.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
N.A.
93.3
86.6
93.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
0
0
0
0
0
0
0
89
0
% E
% Phe:
0
0
89
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
89
0
12
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
23
% I
% Lys:
0
0
0
0
0
0
12
12
45
0
0
0
0
0
0
% K
% Leu:
89
12
12
0
78
0
12
0
0
0
0
12
0
12
0
% L
% Met:
0
0
0
12
0
12
0
0
12
100
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
67
0
0
0
0
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
89
0
0
34
0
0
0
89
0
0
% R
% Ser:
0
0
0
23
0
0
12
0
0
0
78
0
0
0
0
% S
% Thr:
0
0
0
34
0
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
78
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
89
0
0
0
78
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _