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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC1A2
All Species:
19.09
Human Site:
S506
Identified Species:
38.18
UniProt:
P43004
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43004
NP_004162.2
574
62104
S506
S
E
L
D
T
I
D
S
Q
H
R
V
H
E
D
Chimpanzee
Pan troglodytes
XP_508369
707
77362
S639
S
E
L
D
T
I
D
S
Q
H
R
V
H
E
D
Rhesus Macaque
Macaca mulatta
XP_001115008
574
62116
S506
S
E
L
D
T
I
D
S
Q
H
R
V
H
E
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P43006
572
62012
S505
S
E
L
D
T
I
D
S
Q
H
R
M
Q
E
D
Rat
Rattus norvegicus
P31596
573
62088
S505
S
E
L
D
T
I
D
S
Q
H
R
M
H
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507997
821
87933
A752
A
E
L
D
S
I
D
A
H
H
K
G
Q
E
D
Chicken
Gallus gallus
NP_001012917
554
60301
K489
G
I
V
Y
H
L
S
K
A
E
L
D
S
I
D
Frog
Xenopus laevis
NP_001083306
542
59629
R477
A
V
D
W
F
L
D
R
L
R
T
T
T
N
V
Zebra Danio
Brachydanio rerio
NP_956273
561
61248
A491
A
E
L
D
A
L
D
A
Q
H
G
K
T
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011597
543
59133
S443
I
G
A
A
S
I
P
S
A
A
L
I
T
M
L
Nematode Worm
Caenorhab. elegans
Q10901
503
54657
V431
V
K
D
V
S
L
I
V
A
V
D
W
L
L
D
Sea Urchin
Strong. purpuratus
XP_796905
530
58013
R456
T
V
D
W
F
L
D
R
C
R
T
S
I
N
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.1
99.8
N.A.
N.A.
95.1
95.3
N.A.
63.8
84.1
47.5
77.8
N.A.
N.A.
53.4
53.4
51.9
Protein Similarity:
100
81.1
99.8
N.A.
N.A.
98.4
98.6
N.A.
67.4
89.5
66.9
86.2
N.A.
N.A.
71.2
68.8
69.3
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
93.3
N.A.
53.3
6.6
6.6
46.6
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
100
N.A.
80
20
20
73.3
N.A.
N.A.
26.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
9
9
9
0
0
17
25
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
25
59
0
0
75
0
0
0
9
9
0
9
75
% D
% Glu:
0
59
0
0
0
0
0
0
0
9
0
0
0
50
0
% E
% Phe:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
0
0
0
0
0
9
9
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
9
59
0
0
34
0
0
% H
% Ile:
9
9
0
0
0
59
9
0
0
0
0
9
9
9
0
% I
% Lys:
0
9
0
0
0
0
0
9
0
0
9
9
0
0
0
% K
% Leu:
0
0
59
0
0
42
0
0
9
0
17
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
17
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
50
0
0
0
17
0
0
% Q
% Arg:
0
0
0
0
0
0
0
17
0
17
42
0
0
0
0
% R
% Ser:
42
0
0
0
25
0
9
50
0
0
0
9
9
0
0
% S
% Thr:
9
0
0
0
42
0
0
0
0
0
17
9
25
0
0
% T
% Val:
9
17
9
9
0
0
0
9
0
9
0
25
0
0
17
% V
% Trp:
0
0
0
17
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _