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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC1A2
All Species:
22.12
Human Site:
T519
Identified Species:
44.24
UniProt:
P43004
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43004
NP_004162.2
574
62104
T519
E
D
I
E
M
T
K
T
Q
S
I
Y
D
D
M
Chimpanzee
Pan troglodytes
XP_508369
707
77362
T652
E
D
I
E
M
T
K
T
Q
S
I
Y
D
D
M
Rhesus Macaque
Macaca mulatta
XP_001115008
574
62116
T519
E
D
I
E
M
T
K
T
Q
S
I
Y
D
D
M
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P43006
572
62012
T518
E
D
I
E
M
T
K
T
Q
S
I
Y
D
D
K
Rat
Rattus norvegicus
P31596
573
62088
T518
E
D
I
E
M
T
K
T
Q
S
V
Y
D
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507997
821
87933
T765
E
D
I
E
M
T
K
T
Q
S
I
F
D
D
M
Chicken
Gallus gallus
NP_001012917
554
60301
H502
I
D
S
H
H
K
E
H
E
D
I
E
M
T
K
Frog
Xenopus laevis
NP_001083306
542
59629
G490
N
V
L
G
D
S
L
G
A
G
I
V
E
H
L
Zebra Danio
Brachydanio rerio
NP_956273
561
61248
K504
D
D
I
E
M
M
T
K
T
Q
S
Y
Y
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011597
543
59133
L456
M
L
I
V
L
T
A
L
G
L
P
T
N
D
I
Nematode Worm
Caenorhab. elegans
Q10901
503
54657
I444
L
D
R
I
R
T
S
I
N
V
L
G
D
A
M
Sea Urchin
Strong. purpuratus
XP_796905
530
58013
G469
N
V
V
G
D
S
Y
G
A
A
I
V
H
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.1
99.8
N.A.
N.A.
95.1
95.3
N.A.
63.8
84.1
47.5
77.8
N.A.
N.A.
53.4
53.4
51.9
Protein Similarity:
100
81.1
99.8
N.A.
N.A.
98.4
98.6
N.A.
67.4
89.5
66.9
86.2
N.A.
N.A.
71.2
68.8
69.3
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
86.6
N.A.
93.3
13.3
6.6
40
N.A.
N.A.
20
26.6
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
100
26.6
33.3
46.6
N.A.
N.A.
40
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
17
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
75
0
0
17
0
0
0
0
9
0
0
59
67
9
% D
% Glu:
50
0
0
59
0
0
9
0
9
0
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
17
0
0
0
17
9
9
0
9
0
0
0
% G
% His:
0
0
0
9
9
0
0
9
0
0
0
0
9
17
0
% H
% Ile:
9
0
67
9
0
0
0
9
0
0
67
0
0
0
9
% I
% Lys:
0
0
0
0
0
9
50
9
0
0
0
0
0
0
17
% K
% Leu:
9
9
9
0
9
0
9
9
0
9
9
0
0
0
17
% L
% Met:
9
0
0
0
59
9
0
0
0
0
0
0
9
0
42
% M
% Asn:
17
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
50
9
0
0
0
0
0
% Q
% Arg:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
17
9
0
0
50
9
0
0
0
0
% S
% Thr:
0
0
0
0
0
67
9
50
9
0
0
9
0
9
9
% T
% Val:
0
17
9
9
0
0
0
0
0
9
9
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
50
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _